1rsz

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|PDB= 1rsz |SIZE=350|CAPTION= <scene name='initialview01'>1rsz</scene>, resolution 2.20&Aring;
|PDB= 1rsz |SIZE=350|CAPTION= <scene name='initialview01'>1rsz</scene>, resolution 2.20&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=DIH:3-HYDROXY-4-HYDROXYMETHYL-1-(4-OXO-4,4A,5,7A-TETRAHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YLMETHYL)-PYRROLIDINIUM'>DIH</scene>
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|LIGAND= <scene name='pdbligand=DIH:3-HYDROXY-4-HYDROXYMETHYL-1-(4-OXO-4,4A,5,7A-TETRAHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YLMETHYL)-PYRROLIDINIUM'>DIH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span>
|GENE= NP, PNP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= NP, PNP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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|DOMAIN=
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|RELATEDENTRY=[[1rr6|1RR6]], [[1rt9|1RT9]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rsz OCA], [http://www.ebi.ac.uk/pdbsum/1rsz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rsz RCSB]</span>
}}
}}
'''Structure of human purine nucleoside phosphorylase in complex with DADMe-Immucillin-H and sulfate'''
'''Structure of human purine nucleoside phosphorylase in complex with DADMe-Immucillin-H and sulfate'''
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==Disease==
 
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Known diseases associated with this structure: Neutral lipid storage disease with myopathy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=609059 609059]], Nucleoside phosphorylase deficiency, immunodeficiency due to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164050 164050]]
 
==About this Structure==
==About this Structure==
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[[Category: Shi, W.]]
[[Category: Shi, W.]]
[[Category: Tyler, P C.]]
[[Category: Tyler, P C.]]
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[[Category: DIH]]
 
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[[Category: SO4]]
 
[[Category: pnp]]
[[Category: pnp]]
[[Category: transition-state analogue]]
[[Category: transition-state analogue]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:55:45 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:32:29 2008''

Revision as of 20:32, 30 March 2008


PDB ID 1rsz

Drag the structure with the mouse to rotate
, resolution 2.20Å
Ligands: ,
Gene: NP, PNP (Homo sapiens)
Activity: Purine-nucleoside phosphorylase, with EC number 2.4.2.1
Related: 1RR6, 1RT9


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Structure of human purine nucleoside phosphorylase in complex with DADMe-Immucillin-H and sulfate


About this Structure

1RSZ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Sun Mar 30 23:32:29 2008

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