User:Morgane Crausaz/Sandbox

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You may include any references to papers as in: the use of JSmol in Proteopedia ^[1] or to the article describing Jmol ^[2] to the rescue.

Introduction

The lysosome is a membrane-bound organelle which is present in animal cells. those are acidic vesicles and contain more than fifty digestive enzymes as proteases, nucleases, glycosidases, sulfatases, lipases, phosphatases phospholipases and esterases. The lumen’s pH of 4,5 is optimal for the hydrolytic enzymes. Indeed, acidic pH is important for the degradation of intracellular and extracellular compounds.

Particularly, there are enzymes able to cleave phospholipids on a specific site: those enzymes are named: phospholipases. These phospholipases are classified into four types, phospholipase A1, A2, C and D depending on the specific cleavage site of the substrate. Phospholipase A2 cleave the acyl-ester bonds of sn-2 position of glycerophospholipids and they produce free fatty acids.

Function

Structure

Disease

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.