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1rw1
From Proteopedia
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|PDB= 1rw1 |SIZE=350|CAPTION= <scene name='initialview01'>1rw1</scene>, resolution 1.02Å | |PDB= 1rw1 |SIZE=350|CAPTION= <scene name='initialview01'>1rw1</scene>, resolution 1.02Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=IPA:ISOPROPYL ALCOHOL'>IPA</scene> | + | |LIGAND= <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= yffB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 Pseudomonas aeruginosa PAO1]) | |GENE= yffB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 Pseudomonas aeruginosa PAO1]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rw1 OCA], [http://www.ebi.ac.uk/pdbsum/1rw1 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rw1 RCSB]</span> | ||
}} | }} | ||
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[[Category: S2F, Structure 2.Function Project.]] | [[Category: S2F, Structure 2.Function Project.]] | ||
[[Category: Teplyakov, A.]] | [[Category: Teplyakov, A.]] | ||
| - | [[Category: IPA]] | ||
[[Category: s2f]] | [[Category: s2f]] | ||
[[Category: structural genomic]] | [[Category: structural genomic]] | ||
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[[Category: thioredoxin fold]] | [[Category: thioredoxin fold]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:33:41 2008'' |
Revision as of 20:33, 30 March 2008
| |||||||
| , resolution 1.02Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Gene: | yffB (Pseudomonas aeruginosa PAO1) | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
YFFB (PA3664) PROTEIN
Overview
BACKGROUND: The yffB (PA3664) gene of Pseudomonas aeruginosa encodes an uncharacterized protein of 13 kDa molecular weight with a marginal sequence similarity to arsenate reductase from Escherichia coli. The crystal structure determination of YffB was undertaken as part of a structural genomics effort in order to assist with the functional assignment of the protein. RESULTS: The structure was determined at 1.0 A resolution by single-wavelength anomalous diffraction. The fold is very similar to that of arsenate reductase, which is an extension of the thioredoxin fold. CONCLUSION: Given the conservation of the functionally important residues and the ability to bind glutathione, YffB is likely to function as a GSH-dependent thiol reductase.
About this Structure
1RW1 is a Single protein structure of sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.
Reference
Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function., Teplyakov A, Pullalarevu S, Obmolova G, Doseeva V, Galkin A, Herzberg O, Dauter M, Dauter Z, Gilliland GL, BMC Struct Biol. 2004 Mar 8;4:5. PMID:15102337
Page seeded by OCA on Sun Mar 30 23:33:41 2008
Categories: Pseudomonas aeruginosa pao1 | Single protein | Dauter, M. | Dauter, Z. | Doseeva, V. | Galkin, A. | Gilliland, G L. | Herzberg, O. | Obmolova, G. | Pullalarevu, S. | S2F, Structure 2.Function Project. | Teplyakov, A. | S2f | Structural genomic | Structure 2 function project | Thioredoxin fold
