5g4x
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The crystal structure of the SHANK3 N-terminus== |
| - | + | <StructureSection load='5g4x' size='340' side='right' caption='[[5g4x]], [[Resolution|resolution]] 2.17Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5g4x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G4X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5G4X FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5g4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g4x OCA], [http://pdbe.org/5g4x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g4x RCSB], [http://www.ebi.ac.uk/pdbsum/5g4x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g4x ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SHAN3_RAT SHAN3_RAT]] Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Rattus norvegicus]] | ||
[[Category: Barsukov, I]] | [[Category: Barsukov, I]] | ||
[[Category: Zacharchenko, T]] | [[Category: Zacharchenko, T]] | ||
| + | [[Category: Integrin]] | ||
| + | [[Category: Ra]] | ||
| + | [[Category: Shank3]] | ||
| + | [[Category: Structural protein]] | ||
Revision as of 23:39, 25 January 2017
The crystal structure of the SHANK3 N-terminus
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