5hkf
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with 5-phospho-alpha-D-ribosyl 1-diphosphate (PRPP)== | |
| - | + | <StructureSection load='5hkf' size='340' side='right' caption='[[5hkf]], [[Resolution|resolution]] 2.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5hkf]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HKF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hkf OCA], [http://pdbe.org/5hkf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hkf RCSB], [http://www.ebi.ac.uk/pdbsum/5hkf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hkf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PYRE_MYCTU PYRE_MYCTU]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Orotate phosphoribosyltransferase]] | ||
[[Category: Bolognesi, G]] | [[Category: Bolognesi, G]] | ||
[[Category: Donini, S]] | [[Category: Donini, S]] | ||
| - | [[Category: Ferraris, D | + | [[Category: Ferraris, D M]] |
[[Category: Rizzi, M]] | [[Category: Rizzi, M]] | ||
| + | [[Category: De novo pyrimidine nucleotide synthesis]] | ||
| + | [[Category: Oprt]] | ||
| + | [[Category: Prpp complex]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 23:41, 25 January 2017
Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with 5-phospho-alpha-D-ribosyl 1-diphosphate (PRPP)
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