5hq5
From Proteopedia
(Difference between revisions)
Line 1: | Line 1: | ||
- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of fragment bound with Brd4== | |
- | + | <StructureSection load='5hq5' size='340' side='right' caption='[[5hq5]], [[Resolution|resolution]] 1.60Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5hq5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HQ5 FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=64Q:7-METHYL-N-(O-TOLYL)-[1,2,4]TRIAZOLO[4,3-A]PYRIMIDIN-5-AMINE'>64Q</scene></td></tr> | |
- | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hq6|5hq6]], [[5hq7|5hq7]]</td></tr> |
- | [[Category: Xu, Y | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hq5 OCA], [http://pdbe.org/5hq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hq5 RCSB], [http://www.ebi.ac.uk/pdbsum/5hq5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hq5 ProSAT]</span></td></tr> |
- | [[Category: | + | </table> |
+ | == Disease == | ||
+ | [[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity). | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Chen, T T]] | ||
+ | [[Category: Xu, Y C]] | ||
+ | [[Category: Brd4]] | ||
+ | [[Category: Transcription]] |
Revision as of 23:42, 25 January 2017
Crystal structure of fragment bound with Brd4
|
Categories: Chen, T T | Xu, Y C | Brd4 | Transcription