5t0q

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'''Unreleased structure'''
 
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The entry 5t0q is ON HOLD until Paper Publication
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==Crystal structure of the Myc3 N-terminal domain [44-242] in complex with JAZ10 Jas domain [166-192] from arabidopsis==
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<StructureSection load='5t0q' size='340' side='right' caption='[[5t0q]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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Authors: Ke, J., Zhang, F., Brunzelle, J.S., He, S.Y., Xu, H.E., Melcher, K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5t0q]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T0Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T0Q FirstGlance]. <br>
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Description: Crystal structure of the Myc3 N-terminal domain [44-242] in complex with JAZ10 Jas domain [166-192] from arabidopsis
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t0q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t0q OCA], [http://pdbe.org/5t0q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t0q RCSB], [http://www.ebi.ac.uk/pdbsum/5t0q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t0q ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Xu, H.E]]
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== Function ==
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[[http://www.uniprot.org/uniprot/MYC3_ARATH MYC3_ARATH]] Transcription factor involved in tryptophan, jasmonic acid (JA) and other stress-responsive gene regulation. With MYC2 and MYC4, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters.<ref>PMID:12136026</ref> <ref>PMID:21242320</ref> <ref>PMID:21321051</ref> <ref>PMID:21335373</ref> <ref>PMID:23943862</ref> [[http://www.uniprot.org/uniprot/TIF9_ARATH TIF9_ARATH]] Modulator of growth inhibition. Isoform 2 and isoform 3, but not isoform 1, confer a strong methyl-jasmonate insensitivity. Not involved in the growth response to salicylic acid or indole-3-acetic acid. Isoform 3 acts as an endogenous repressor of JA signal output in JA-stimulated cells (PubMed:19151223).<ref>PMID:17675405</ref> <ref>PMID:19151223</ref> <ref>PMID:23632853</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Brunzelle, J S]]
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[[Category: He, S Y]]
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[[Category: Ke, J]]
[[Category: Melcher, K]]
[[Category: Melcher, K]]
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[[Category: He, S.Y]]
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[[Category: Xu, H E]]
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[[Category: Brunzelle, J.S]]
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[[Category: Zhang, F]]
[[Category: Zhang, F]]
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[[Category: Ke, J]]
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[[Category: Alternative splicing]]
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[[Category: Desensitization]]
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[[Category: Jasmonate signaling]]
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[[Category: Jaz10 cmid]]
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[[Category: Myc3]]
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[[Category: Transcription]]
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[[Category: Transcriptional repression]]

Revision as of 23:46, 25 January 2017

Crystal structure of the Myc3 N-terminal domain [44-242] in complex with JAZ10 Jas domain [166-192] from arabidopsis

5t0q, resolution 2.15Å

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