5tjb
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==I-II linker of TRPML1 channel at pH 4.5== | |
| - | + | <StructureSection load='5tjb' size='340' side='right' caption='[[5tjb]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5tjb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TJB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TJB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tja|5tja]], [[5tjc|5tjc]]</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tjb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tjb OCA], [http://pdbe.org/5tjb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tjb RCSB], [http://www.ebi.ac.uk/pdbsum/5tjb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tjb ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/MCLN1_HUMAN MCLN1_HUMAN]] Mucolipidosis type 4. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MCLN1_HUMAN MCLN1_HUMAN]] Cation channel probably playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. Could play a major role in Ca(2+) transport regulating lysosomal exocytosis.<ref>PMID:12459486</ref> <ref>PMID:14749347</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Benvin, N M]] | ||
| + | [[Category: Li, H]] | ||
| + | [[Category: Li, M]] | ||
| + | [[Category: Li, X]] | ||
| + | [[Category: Michailidis, I E]] | ||
| + | [[Category: Su, D]] | ||
| + | [[Category: Tong, L]] | ||
| + | [[Category: Wang, S]] | ||
| + | [[Category: Yang, J]] | ||
| + | [[Category: Zhang, W K]] | ||
| + | [[Category: Zhou, X]] | ||
| + | [[Category: Calcium and ph regulation]] | ||
| + | [[Category: Endolysosomal lumen]] | ||
| + | [[Category: Tetramer]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 23:46, 25 January 2017
I-II linker of TRPML1 channel at pH 4.5
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Categories: Benvin, N M | Li, H | Li, M | Li, X | Michailidis, I E | Su, D | Tong, L | Wang, S | Yang, J | Zhang, W K | Zhou, X | Calcium and ph regulation | Endolysosomal lumen | Tetramer | Transport protein
