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4wrs
From Proteopedia
(Difference between revisions)
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==Crystal structure of human Pim-1 kinase in complex with an azaspiro pyrazinyl-indazole inhibitor.== | ==Crystal structure of human Pim-1 kinase in complex with an azaspiro pyrazinyl-indazole inhibitor.== | ||
<StructureSection load='4wrs' size='340' side='right' caption='[[4wrs]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='4wrs' size='340' side='right' caption='[[4wrs]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3U1:3-{6-[(4R)-6-AZASPIRO[2.5]OCT-4-YLOXY]PYRAZIN-2-YL}-5-(2,6-DIFLUOROPHENYL)-1H-INDAZOLE'>3U1</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3U1:3-{6-[(4R)-6-AZASPIRO[2.5]OCT-4-YLOXY]PYRAZIN-2-YL}-5-(2,6-DIFLUOROPHENYL)-1H-INDAZOLE'>3U1</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wrs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wrs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wrs RCSB], [http://www.ebi.ac.uk/pdbsum/4wrs PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wrs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wrs OCA], [http://pdbe.org/4wrs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wrs RCSB], [http://www.ebi.ac.uk/pdbsum/4wrs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wrs ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4wrs" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 00:09, 26 January 2017
Crystal structure of human Pim-1 kinase in complex with an azaspiro pyrazinyl-indazole inhibitor.
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