Mitogen-activated protein kinase kinase kinase

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<StructureSection load='2o2v' size='350' side='right' caption='Mitogen-activated protein kinase kinase kinase 3 (green) complex with MAP2K5 PHOX domain (grey) (PDB code [[2o2v]]).' scene=''>
<StructureSection load='2o2v' size='350' side='right' caption='Mitogen-activated protein kinase kinase kinase 3 (green) complex with MAP2K5 PHOX domain (grey) (PDB code [[2o2v]]).' scene=''>
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MAP3K1 mutations are observed in various cancer types and in particular in luminal beast cancer.
MAP3K1 mutations are observed in various cancer types and in particular in luminal beast cancer.
</StructureSection>
</StructureSection>
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== 3D Structures of Mitogen-activated protein kinase kinase ==
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== 3D Structures of Mitogen-activated protein kinase kinase kinase==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}

Revision as of 10:50, 29 January 2017

Mitogen-activated protein kinase kinase kinase 3 (green) complex with MAP2K5 PHOX domain (grey) (PDB code 2o2v).

Drag the structure with the mouse to rotate

3D Structures of Mitogen-activated protein kinase kinase kinase

Updated on 29-January-2017

References

  1. Ellinger-Ziegelbauer H, Brown K, Kelly K, Siebenlist U. Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 (MEKK) derivative. J Biol Chem. 1997 Jan 31;272(5):2668-74. PMID:9006902

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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