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2fv9

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==Crystal stucture of TACE in complex with JMV 390-1==
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==Crystal structure of TACE in complex with JMV 390-1==
<StructureSection load='2fv9' size='340' side='right' caption='[[2fv9]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
<StructureSection load='2fv9' size='340' side='right' caption='[[2fv9]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2fv9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FV9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FV9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2fv9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FV9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FV9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=002:N-[(2R)-2-BENZYL-4-(HYDROXYAMINO)-4-OXOBUTANOYL]-L-ISOLEUCYL-L-LEUCINE'>002</scene>, <scene name='pdbligand=INN:N-{(2R)-2-[2-(HYDROXYAMINO)-2-OXOETHYL]-4-METHYLPENTANOYL}-3-METHYL-L-VALYL-N-(2-AMINOETHYL)-L-ALANINAMIDE'>INN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=002:N-[(2R)-2-BENZYL-4-(HYDROXYAMINO)-4-OXOBUTANOYL]-L-ISOLEUCYL-L-LEUCINE'>002</scene>, <scene name='pdbligand=INN:N-{(2R)-2-[2-(HYDROXYAMINO)-2-OXOETHYL]-4-METHYLPENTANOYL}-3-METHYL-L-VALYL-N-(2-AMINOETHYL)-L-ALANINAMIDE'>INN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bkc|1bkc]], [[2ddf|2ddf]], [[2fv5|2fv5]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bkc|1bkc]], [[2ddf|2ddf]], [[2fv5|2fv5]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADAM17, CSVP, TACE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
 
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ADAM_17_endopeptidase ADAM 17 endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.86 3.4.24.86] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ADAM_17_endopeptidase ADAM 17 endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.86 3.4.24.86] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fv9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fv9 OCA], [http://pdbe.org/2fv9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fv9 RCSB], [http://www.ebi.ac.uk/pdbsum/2fv9 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fv9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fv9 OCA], [http://pdbe.org/2fv9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fv9 RCSB], [http://www.ebi.ac.uk/pdbsum/2fv9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fv9 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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</div>
</div>
<div class="pdbe-citations 2fv9" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2fv9" style="background-color:#fffaf0;"></div>
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==See Also==
 
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*[[A Disintegrin And Metalloproteinase|A Disintegrin And Metalloproteinase]]
 
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: ADAM 17 endopeptidase]]
[[Category: ADAM 17 endopeptidase]]
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[[Category: Human]]
 
[[Category: Orth, P]]
[[Category: Orth, P]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Tace adam33 zn-endopeptidase]]
[[Category: Tace adam33 zn-endopeptidase]]

Revision as of 10:56, 1 February 2017

Crystal structure of TACE in complex with JMV 390-1

2fv9, resolution 2.02Å

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