5hu3

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'''Unreleased structure'''
 
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The entry 5hu3 is ON HOLD until Paper Publication
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==Drosophila CaMKII-D136N in complex with a phosphorylated fragment of the Eag potassium channel and Mg2+/ADP==
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<StructureSection load='5hu3' size='340' side='right' caption='[[5hu3]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5hu3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HU3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HU3 FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fg8|5fg8]], [[5h9b|5h9b]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hu3 OCA], [http://pdbe.org/5hu3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hu3 RCSB], [http://www.ebi.ac.uk/pdbsum/5hu3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hu3 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/KCC2A_DROME KCC2A_DROME]] A key regulator of plasticity in synaptic physiology and behavior, alterations in its activity produce pleiotrophic effects that involve synaptic transmission and development as well as various aspects of behavior. Directly modulates eag potassium channels.<ref>PMID:11980904</ref> <ref>PMID:14687552</ref> [[http://www.uniprot.org/uniprot/KCNAE_DROME KCNAE_DROME]] Structural component of a potassium channel. Mediates the potassium permeability of membranes; potassium current is regulated by CaMKII and CASK. Has a role in growth of the perineurial glial layer of the larval peripheral nerve.<ref>PMID:11517334</ref> <ref>PMID:11980904</ref> <ref>PMID:15901771</ref> <ref>PMID:1840699</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Calcium/calmodulin-dependent protein kinase]]
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[[Category: Castro-Rodrigues, A F]]
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[[Category: Morais-Cabral, J H]]
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[[Category: Complex]]
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[[Category: Potassium channel]]
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[[Category: Protein kinase]]
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[[Category: Transferase]]

Revision as of 18:05, 1 February 2017

Drosophila CaMKII-D136N in complex with a phosphorylated fragment of the Eag potassium channel and Mg2+/ADP

5hu3, resolution 1.89Å

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