5hxu

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'''Unreleased structure'''
 
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The entry 5hxu is ON HOLD until Paper Publication
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==Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes==
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<StructureSection load='5hxu' size='340' side='right' caption='[[5hxu]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
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Authors: Peat, T.S., Balotra, S., Wilding, M., Newman, J., Scott, C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5hxu]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HXU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HXU FirstGlance]. <br>
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Description: Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MHA:(CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC+ACID'>MHA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hwe|5hwe]], [[5hxz|5hxz]], [[5hy0|5hy0]], [[5hy1|5hy1]], [[5hy2|5hy2]], [[5hy4|5hy4]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Barbiturase Barbiturase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.1 3.5.2.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hxu OCA], [http://pdbe.org/5hxu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hxu RCSB], [http://www.ebi.ac.uk/pdbsum/5hxu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hxu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/BAR_RHOER BAR_RHOER]] Cleaves the barbituric acid ring to yield ureidomalonic acid.<ref>PMID:11485332</ref> <ref>PMID:11748240</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Barbiturase]]
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[[Category: Balotra, S]]
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[[Category: Newman, J]]
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[[Category: Peat, T S]]
[[Category: Scott, C]]
[[Category: Scott, C]]
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[[Category: Peat, T.S]]
 
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[[Category: Newman, J]]
 
[[Category: Wilding, M]]
[[Category: Wilding, M]]
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[[Category: Balotra, S]]
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[[Category: Hydrolase]]
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[[Category: Pyrimidine catabolism]]
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[[Category: Toblerone fold]]

Revision as of 18:05, 1 February 2017

Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes

5hxu, resolution 1.83Å

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