1s9b
From Proteopedia
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|PDB= 1s9b |SIZE=350|CAPTION= <scene name='initialview01'>1s9b</scene>, resolution 2.81Å | |PDB= 1s9b |SIZE=350|CAPTION= <scene name='initialview01'>1s9b</scene>, resolution 2.81Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=NI:NICKEL (II) ION'>NI</scene> | + | |LIGAND= <scene name='pdbligand=DA:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5'-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s9b OCA], [http://www.ebi.ac.uk/pdbsum/1s9b PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1s9b RCSB]</span> | ||
}} | }} | ||
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[[Category: Uson, I.]] | [[Category: Uson, I.]] | ||
[[Category: Valls, N.]] | [[Category: Valls, N.]] | ||
| - | [[Category: NI]] | ||
[[Category: cubic dna]] | [[Category: cubic dna]] | ||
[[Category: double helix]] | [[Category: double helix]] | ||
[[Category: nickel]] | [[Category: nickel]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:39:01 2008'' |
Revision as of 20:39, 30 March 2008
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| , resolution 2.81Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure Analysis of the B-DNA GAATTCG
Overview
DNA oligonucleotides can be used in order to assemble highly structured materials. Oligonucleotides with sticky ends can form long linear structures, whereas branching is required to form two- and three-dimensional nanostructures. In this paper, we show that when Ni(2+) is attached to the N7 atom of guanine, it can also act as a branching point. Thus, we have found that the heptanucleotide d(GAATTCG) can assemble into long linear duplex structures, which cross in space to generate a cubic structure. The three-dimensional arrays are stabilized by phosphate-Ni(2+)-guanine interactions. For the first time, the crystallization of a B form DNA oligonucleotide in a cubic system is reported, space group I23. Large solvent cavities are found among the DNA duplexes.
About this Structure
1S9B is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
A cubic arrangement of DNA double helices based on nickel-guanine interactions., Valls N, Uson I, Gouyette C, Subirana JA, J Am Chem Soc. 2004 Jun 30;126(25):7812-6. PMID:15212528
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