4gis
From Proteopedia
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==crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, glycerol and dicarboxylates bound (mixed loops, space group I4122)== | ==crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, glycerol and dicarboxylates bound (mixed loops, space group I4122)== | ||
<StructureSection load='4gis' size='340' side='right' caption='[[4gis]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='4gis' size='340' side='right' caption='[[4gis]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAE:MALEIC+ACID'>MAE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAE:MALEIC+ACID'>MAE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VME_00770 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=673519 Vibrio harveyi 1DA3])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VME_00770 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=673519 Vibrio harveyi 1DA3])</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gis OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gis RCSB], [http://www.ebi.ac.uk/pdbsum/4gis PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gis OCA], [http://pdbe.org/4gis PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gis RCSB], [http://www.ebi.ac.uk/pdbsum/4gis PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gis ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/IMAND_VIBHA IMAND_VIBHA]] Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.<ref>PMID:24697546</ref> | [[http://www.uniprot.org/uniprot/IMAND_VIBHA IMAND_VIBHA]] Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.<ref>PMID:24697546</ref> | ||
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| - | ==See Also== | ||
| - | *[[Enolase|Enolase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 18:38, 1 February 2017
crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, glycerol and dicarboxylates bound (mixed loops, space group I4122)
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Categories: Vibrio harveyi 1da3 | Almo, S C | Bhosle, R | Chowdhury, S | EFI, Enzyme Function Initiative | Evans, B | Gerlt, J A | Glenn, A Scott | Hammonds, J | Hillerich, B | Imker, H J | Love, J | Morisco, L L | Obaidi, N F.Al | Seidel, R D | Sojitra, S | Toro, R | Vetting, M W | Washington, E | Wasserman, S R | Efi | Enolase | Enzyme function initiative | Lyase | Putative mannonate dehydratase | Structural genomic
