Rho GTPase
From Proteopedia
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(New page: <StructureSection load='5c4m' size='340' side='right' caption='Caption for this structure' scene=''> == Function == '''Rho GTPase''' of higher vertebrates include '''RhoA, RhoB''' and '...) |
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<StructureSection load='5c4m' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='5c4m' size='340' side='right' caption='Caption for this structure' scene=''> | ||
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== Disease == | == Disease == | ||
| + | Mutations in RhoA were identified in diffuse gastric cancer<ref>PMID:25026207</ref>. | ||
== Relevance == | == Relevance == | ||
| + | RhoA is thought to be important in mediating vasoconstriction in the penis<ref>PMID:16411892</ref>. | ||
== Structural highlights == | == Structural highlights == | ||
Revision as of 07:55, 8 February 2017
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3D structures of Rho GTPase
Updated on 08-February-2017
References
- ↑ Sepp KJ, Auld VJ. RhoA and Rac1 GTPases mediate the dynamic rearrangement of actin in peripheral glia. Development. 2003 May;130(9):1825-35. PMID:12642488
- ↑ Zhou J, Hayakawa Y, Wang TC, Bass AJ. RhoA mutations identified in diffuse gastric cancer. Cancer Cell. 2014 Jul 14;26(1):9-11. doi: 10.1016/j.ccr.2014.06.022. PMID:25026207 doi:http://dx.doi.org/10.1016/j.ccr.2014.06.022
- ↑ Jin L, Burnett AL. RhoA/Rho-kinase in erectile tissue: mechanisms of disease and therapeutic insights. Clin Sci (Lond). 2006 Feb;110(2):153-65. PMID:16411892 doi:http://dx.doi.org/10.1042/CS20050255
