Sandbox Reserved 1273
From Proteopedia
| Line 3: | Line 3: | ||
<Structure load='3cw6' size='350' frame='true' align='right' caption='This is the three-dimensional structure of the tRNA fMet molecule' scene='Insert optional scene name here' /> | <Structure load='3cw6' size='350' frame='true' align='right' caption='This is the three-dimensional structure of the tRNA fMet molecule' scene='Insert optional scene name here' /> | ||
| + | |||
| + | ==Function== | ||
| + | |||
| + | tRNA fMet is the tRNA used for the initiation of protein synthesis. It is the fist tRNA molecule that enters the ribosome, specifically at the P site, as opposed to all other tRNAs which enter the A site. The amino acid attached to tRNA fMet is N-formylmethionine, which is the first amino acid assembled into the polypeptide chain during bacterial translation. It corresponds to the start codon, "AUG." Additional amino acids then bond with the N-formylmethionine attached to tRNA fMet, in order to assemble a protein. In this way, tRNA fMet is one of the molecules that begins the process of converting genetic code to protein. | ||
==tRNA-fmet and Ribosome Interaction== | ==tRNA-fmet and Ribosome Interaction== | ||
tRNA fmet attaches to the initiation codon which requires initiation factor 2 (IF-2) and forms a complex with GTP. This complex is collectively referred to as the 30S initiation complex. | tRNA fmet attaches to the initiation codon which requires initiation factor 2 (IF-2) and forms a complex with GTP. This complex is collectively referred to as the 30S initiation complex. | ||
Revision as of 20:29, 8 February 2017
tRNA fMet
|
Function
tRNA fMet is the tRNA used for the initiation of protein synthesis. It is the fist tRNA molecule that enters the ribosome, specifically at the P site, as opposed to all other tRNAs which enter the A site. The amino acid attached to tRNA fMet is N-formylmethionine, which is the first amino acid assembled into the polypeptide chain during bacterial translation. It corresponds to the start codon, "AUG." Additional amino acids then bond with the N-formylmethionine attached to tRNA fMet, in order to assemble a protein. In this way, tRNA fMet is one of the molecules that begins the process of converting genetic code to protein.
tRNA-fmet and Ribosome Interaction
tRNA fmet attaches to the initiation codon which requires initiation factor 2 (IF-2) and forms a complex with GTP. This complex is collectively referred to as the 30S initiation complex.
