Sandbox Reserved 1304
From Proteopedia
(Difference between revisions)
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''What it interacts with:'' This polymerase interacts with Pol III holoenzyme processivity, and occasionally has been proven to bypass N2-deoxyguanine adducts. It also repairs base-pair lesions, and connects directly to the DNA. | ''What it interacts with:'' This polymerase interacts with Pol III holoenzyme processivity, and occasionally has been proven to bypass N2-deoxyguanine adducts. It also repairs base-pair lesions, and connects directly to the DNA. | ||
| - | ''Where it interacts:'' It acts at stalled replication forks in the DNA of E. Coli; though it is poorly processive, it allows stationary-phase adaptive mutation, which provides the bacterium flexibility in dealing with environmental stress. <scene name='75/751197/Ser42/1'>Ser42</scene> residue in the active site reacts with base pairs on the DNA directly, close to the minor groove. | + | ''Where it interacts:'' It acts at stalled replication forks in the DNA of E. Coli; though it is poorly processive, it allows stationary-phase adaptive mutation, which provides the bacterium flexibility in dealing with environmental stress. <scene name='75/751197/Ser42/1'>Ser42</scene> residue (shown in yellow on our scene) in the active site reacts with base pairs on the DNA directly, close to the minor groove. |
== Origin == | == Origin == | ||
The only organism in which DNA Polymerase IV originates is E. coli bacteria. | The only organism in which DNA Polymerase IV originates is E. coli bacteria. | ||
Current revision
DNA Polymerase IV (PolIV)
This is as it closely interacts with .
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