3-phosphoinositide-dependent protein kinase 1

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**[[5lvm]] – hPdk1 (mutant) + adenine + PSer <br />
**[[5lvm]] – hPdk1 (mutant) + adenine + PSer <br />
**[[5lvn]] – hPdk1 (mutant) + adenosine + PSer <br />
**[[5lvn]] – hPdk1 (mutant) + adenosine + PSer <br />
-
**[[4rqk]], [[4rqv]] – hPdk1 (mutant) + ATP + PSer + inhibitor<br />
+
**[[4rqk]], [[4rqv]], [[5mrd]] – hPdk1 (mutant) + ATP + PSer + inhibitor<br />
**[[4rrv]] – hPdk1 (mutant) + ATP + PSer + serine/threonine protein kinase N2<br />
**[[4rrv]] – hPdk1 (mutant) + ATP + PSer + serine/threonine protein kinase N2<br />
**[[3hrf]], [[4a06]], [[4a07]], [[4aw0]], [[4aw1]] – hPdk1 (mutant) + PSer + ATP + activator<br />
**[[3hrf]], [[4a06]], [[4a07]], [[4aw0]], [[4aw1]] – hPdk1 (mutant) + PSer + ATP + activator<br />

Revision as of 09:40, 14 February 2017

Human Pdk1 kinase domain containing phosphorylated serine 241 complex with pyrazoloquinazoline inhibitor, sulfate and glycerol (PDB entry 2xch)

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3D Structures of Pdk1

Updated on 14-February-2017

References

  1. Mora A, Komander D, van Aalten DM, Alessi DR. PDK1, the master regulator of AGC kinase signal transduction. Semin Cell Dev Biol. 2004 Apr;15(2):161-70. PMID:15209375

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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