Mutations in BRCA1/BARD1 RING-domain heterodimer
From Proteopedia
(Difference between revisions)
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==Pathogenic mutations== | ==Pathogenic mutations== | ||
*<scene name='75/751104/Cv/21'>Pathogenic mutations in RING domain</scene>. | *<scene name='75/751104/Cv/21'>Pathogenic mutations in RING domain</scene>. | ||
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*<scene name='75/751104/L22s/3'>Mutation L22S: </scene> | *<scene name='75/751104/L22s/3'>Mutation L22S: </scene> | ||
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<jmolLink> | <jmolLink> | ||
<script> | <script> | ||
| - | animation off; frame all | + | animation off; frame all; select [SER]22;color selectionHalos red;selectionHalos on; |
</script> | </script> | ||
<text>mutated and wild type | <text>mutated and wild type | ||
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<jmolLink> | <jmolLink> | ||
<script> | <script> | ||
| - | animation on; animation mode loop; frame play | + | animation on; animation mode loop; frame play; select [SER]22;color selectionHalos red;selectionHalos on; |
</script> | </script> | ||
<text>animation | <text>animation | ||
Revision as of 08:57, 16 February 2017
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References
- ↑ Brzovic PS, Rajagopal P, Hoyt DW, King MC, Klevit RE. Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat Struct Biol. 2001 Oct;8(10):833-7. PMID:11573085 doi:10.1038/nsb1001-833
Proteopedia Page Contributors and Editors (what is this?)
Alexander Berchansky, Michal Harel, Jaime Prilusky, Joel L. Sussman
