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Actin

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Line 19: Line 19:
* α actin 1 (Aa)
* α actin 1 (Aa)
 +
 +
**[[3hbt]], [[2zwh]], [[1nwk]], [[1j6z]], [[3g37]], [[2y83]] – rAa – rabbit<br />
 +
**[[2q1n]], [[2q31]], [[2a5x]], [[1rdw]], [[1rfq]], [[1lcu]] – rAa – dimer<br />
 +
**[[3mfp]], [[4a7n]], [[3j8i]], [[3j8j]], [[3j8k]], [[3jbj]] – rAa – Cryo EM<br />
 +
**[[2hmp]] – rAa – protease cleaved<br />
 +
**[[2zwh]], [[2gwj]], [[2gwk]] – rAa-ATP<br />
 +
**[[3j8i]], [[3j8j]], [[3j8k]] – rAa + ADP – Cryo EM<br />
 +
**[[3b5u]] – rAa filament – fiber diffraction<br />
 +
 +
* α actin 1 complex
**[[2w49]] – cAa +troponin C+ troponin T+ troponin I+ tropomyosin α-1 – chicken<br />
**[[2w49]] – cAa +troponin C+ troponin T+ troponin I+ tropomyosin α-1 – chicken<br />
Line 24: Line 34:
**[[1mdu]] – cAa+hGelsolin<br />
**[[1mdu]] – cAa+hGelsolin<br />
**[[3j8a]] - mAa + tropomyosin - mouse<br />
**[[3j8a]] - mAa + tropomyosin - mouse<br />
-
**[[3hbt]], [[2zwh]], [[1nwk]], [[1j6z]], [[3g37]], [[2y83]] – rAa – rabbit<br />
+
**[[4a7f]], [[4a7h]], [[4a7l]], [[5h53]], [[5kg8]] – rAa + tropomyosin α-1 + myosin heavy chain (mutant) – Cryo EM<br />
-
**[[4a7f]], [[4a7h]], [[4a7l]] – rAa + tropomyosin α-1 + myosin heavy chain (mutant) – Cryo EM<br />
+
**[[5jlf]], [[3j8a]] – rAa + tropomyosin alpha-1 + ADP Cryo EM<br />
-
**[[2q1n]], [[2q31]], [[2a5x]], [[1rdw]], [[1rfq]], [[1lcu]] – rAa – dimer<br />
+
**[[3mfp]], [[4a7n]], [[3j8i]], [[3j8j]], [[3j8k]] – rAa – Cryo EM<br />
**[[3mfp]], [[4a7n]], [[3j8i]], [[3j8j]], [[3j8k]] – rAa – Cryo EM<br />
**[[2q36]], [[1qz5]] – rAa+kabiramide C – dimer<br />
**[[2q36]], [[1qz5]] – rAa+kabiramide C – dimer<br />
-
**[[2hmp]] – rAa – protease cleaved<br />
 
-
**[[2zwh]], [[2gwj]], [[2gwk]] – rAa-ATP<br />
 
**[[2vyp]] – rAa+myxobacterial rhizopodin<br />
**[[2vyp]] – rAa+myxobacterial rhizopodin<br />
**[[2v51]], [[2v52]], [[2yje]], [[2yjf]] – rAa+mMKL/Myocardin-like protein – mouse (m)<br />
**[[2v51]], [[2v52]], [[2yje]], [[2yjf]] – rAa+mMKL/Myocardin-like protein – mouse (m)<br />
Line 40: Line 47:
**[[3daw]] – rAa+mTwinfilin-1<br />
**[[3daw]] – rAa+mTwinfilin-1<br />
**[[3buz]] – rAa+Iota toxin component IA<br />
**[[3buz]] – rAa+Iota toxin component IA<br />
-
**[[3b5u]] – rAa filament – fiber diffraction<br />
 
**[[1eqy]], [[3cjb]], [[1p8z]], [[3ffk]], [[3tu5]], [[4pkg]], [[4pkh]], [[4pki]] – rAa+hGelsolin<br />
**[[1eqy]], [[3cjb]], [[1p8z]], [[3ffk]], [[3tu5]], [[4pkg]], [[4pkh]], [[4pki]] – rAa+hGelsolin<br />
**[[4b1u]], [[4b1v]], [[4b1w]], [[4b1x]], [[4b1y]], [[4b1z]] – rAa + phosphatase and actin regulator<br />
**[[4b1u]], [[4b1v]], [[4b1w]], [[4b1x]], [[4b1y]], [[4b1z]] – rAa + phosphatase and actin regulator<br />
**[[1rgi]] - rAa+hoGelsolin – horse (ho)<br />
**[[1rgi]] - rAa+hoGelsolin – horse (ho)<br />
**[[1t44]] - rAa+hGelsolin:mThymosin β-4 <br />
**[[1t44]] - rAa+hGelsolin:mThymosin β-4 <br />
 +
**[[4z94]] - rAa+hGelsolin/tropomodulin/leiomodin<br />
**[[4pl8]] - rAa+ Thymosin β-4<br />
**[[4pl8]] - rAa+ Thymosin β-4<br />
**[[3u8x]] - rAa+DmThymosin β-4 - ''Drosophila melanogaster''<br />
**[[3u8x]] - rAa+DmThymosin β-4 - ''Drosophila melanogaster''<br />
Line 76: Line 83:
**[[3ue5]] – rAa + spire domain D<br />
**[[3ue5]] – rAa + spire domain D<br />
**[[4gy2]] – rAa + ι toxin component IA <br />
**[[4gy2]] – rAa + ι toxin component IA <br />
 +
**[[3jbi]] – rAa + vinculin - CryoEM <br />
 +
**[[3jbk]] – rAa + metavinculin + ADP - CryoEM <br />
 +
**[[4wyb]] – rAa + BUD6 <br />
 +
**[[4v0u]] – rAa + protein phosphatase 1 +serine/threonine protein phosphatase <br />
**[[4h0t]] – rAa + ι toxin component IA + ADPR<br />
**[[4h0t]] – rAa + ι toxin component IA + ADPR<br />
**[[4h03]], [[4h0v]], [[4h0x]], [[4h0y]] – rAa + ι toxin component IA + NAD<br />
**[[4h03]], [[4h0v]], [[4h0x]], [[4h0y]] – rAa + ι toxin component IA + NAD<br />
Line 81: Line 92:
**[[4cbu]] – Aa + gelsolin – ''Plasmodium falciparum''<br />
**[[4cbu]] – Aa + gelsolin – ''Plasmodium falciparum''<br />
**[[4cbw]] – PbAa + gelsolin – ''Plasmodium berghei''<br />
**[[4cbw]] – PbAa + gelsolin – ''Plasmodium berghei''<br />
 +
**[[5i9e]] – yAa + actin-related protein 4 + helicase <br />
 +
**[[5ce3]], [[4ci6]] – Aa + protein kinase YopO – fall armyworm <br />
* β actin (Ab)
* β actin (Ab)
Line 86: Line 99:
**[[3lue]] – hAb+hAlpha-actinin <br />
**[[3lue]] – hAb+hAlpha-actinin <br />
**[[3byh]] – hAb+hFimbrin ABD2 – Cryo EM<br />
**[[3byh]] – hAb+hFimbrin ABD2 – Cryo EM<br />
 +
**[[3j82]] – hAb + DNGR-1 - CryoEM <br />
**[[2oan]] – cAb<br />
**[[2oan]] – cAb<br />
**[[3j0s]] – cAb + cofilin 2<br />
**[[3j0s]] – cAb + cofilin 2<br />
Line 102: Line 116:
**[[1d4x]] – Ag 1/3+hGelsolin – ''C. elegans''<br />
**[[1d4x]] – Ag 1/3+hGelsolin – ''C. elegans''<br />
**[[1h1v]] – hAg+rGelsolin<br />
**[[1h1v]] – hAg+rGelsolin<br />
 +
**[[5jlh]] – hAg + myosin-14 + tropomyosin alpha-3 – Cryo-EM <br />
**[[1hlu]], [[2btf]] – cAg+cProfilin<br />
**[[1hlu]], [[2btf]] – cAg+cProfilin<br />
**[[1o1g]], [[1o1a]], [[1o1b]], [[1o1c]], [[1o1d]], [[1o1e]], [[1o1f]], [[1o18]], [[1o19]], [[1mvw]], [[1m8q]] –cAg+cMyosin II - tomography<br />
**[[1o1g]], [[1o1a]], [[1o1b]], [[1o1c]], [[1o1d]], [[1o1e]], [[1o1f]], [[1o18]], [[1o19]], [[1mvw]], [[1m8q]] –cAg+cMyosin II - tomography<br />
Line 114: Line 129:
**[[3mmv]] – DmA-5C+spire WH2 domain<br />
**[[3mmv]] – DmA-5C+spire WH2 domain<br />
**[[3mn6]], [[3mn7]], [[3mn9]] - DmA-5C (mutant)+spire<br />
**[[3mn6]], [[3mn7]], [[3mn9]] - DmA-5C (mutant)+spire<br />
 +
 +
*Actin 5C (A5C)
 +
 +
**[[4rwt]] – DmA5C + leiomodin<br />
 +
**[[4efh]] – A + spire domains C,D – ''Acanthamoeba castellanii''
**[[4efh]] – A + spire domains C,D – ''Acanthamoeba castellanii''
}}
}}

Revision as of 10:05, 21 February 2017

Native G-actin with methyl-histidine complex with ATP, sulfate and Ca+2 ion (green) 3hbt

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3D Structures of Actin

Updated on 21-February-2017

Reference

  1. Otterbein LR, Graceffa P, Dominguez R. The crystal structure of uncomplexed actin in the ADP state. Science. 2001 Jul 27;293(5530):708-11. PMID:11474115 doi:10.1126/science.1059700
  2. Wang H, Robinson RC, Burtnick LD. The structure of native G-actin. Cytoskeleton (Hoboken). 2010 Jul;67(7):456-65. PMID:20540085 doi:10.1002/cm.20458

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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