Adenylosuccinate lyase
From Proteopedia
(Difference between revisions)
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**[[5eyv]] – SmASL – ''Schistosoma mansoni''<br /> | **[[5eyv]] – SmASL – ''Schistosoma mansoni''<br /> | ||
**[[4nle]] – ASL – ''Mycobacterium smegmatis''<br /> | **[[4nle]] – ASL – ''Mycobacterium smegmatis''<br /> | ||
| - | **[[ | + | **[[4ffc]] – hASL (mutant) – human<br /> |
**[[5e3v]], [[4nsl]] – ASL – ''Salmonella typhimurium''<br /> | **[[5e3v]], [[4nsl]] – ASL – ''Salmonella typhimurium''<br /> | ||
**[[3gzh]], [[2pts]] – EcASL – ''Escherichia coli''<br /> | **[[3gzh]], [[2pts]] – EcASL – ''Escherichia coli''<br /> | ||
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**[[2ptr]] – EcASL (mutant) + substrate <br /> | **[[2ptr]] – EcASL (mutant) + substrate <br /> | ||
**[[2pfm]] – ASL + malonate – ''Bacillus anthracis''<br /> | **[[2pfm]] – ASL + malonate – ''Bacillus anthracis''<br /> | ||
| - | **[[5e3v]] – FtASL + fumarate - ''Francisella tularensis'' <br /> | + | **[[5e3v]], [[5hw2]] – FtASL + fumarate - ''Francisella tularensis'' <br /> |
*Adenylosuccinate lyase higher complexes | *Adenylosuccinate lyase higher complexes | ||
Revision as of 08:14, 22 February 2017
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3D structures of adenylosuccinate lyase
Updated on 22-February-2017
References
- ↑ Kmoch S, Hartmannova H, Stiburkova B, Krijt J, Zikanova M, Sebesta I. Human adenylosuccinate lyase (ADSL), cloning and characterization of full-length cDNA and its isoform, gene structure and molecular basis for ADSL deficiency in six patients. Hum Mol Genet. 2000 Jun 12;9(10):1501-13. PMID:10888601
- ↑ Mierzewska H, Schmidt-Sidor B, Jurkiewicz E, Bogdanska A, Kusmierska K, Stepien T. Severe encephalopathy with brain atrophy and hypomyelination due to adenylosuccinate lyase deficiency--MRI, clinical, biochemical and neuropathological findings of Polish patients. Folia Neuropathol. 2009;47(4):314-20. PMID:20054783
- ↑ Fyfe PK, Dawson A, Hutchison MT, Cameron S, Hunter WN. Structure of Staphylococcus aureus adenylosuccinate lyase (PurB) and assessment of its potential as a target for structure-based inhibitor discovery. Acta Crystallogr D Biol Crystallogr. 2010 Aug;66(Pt 8):881-8. Epub 2010, Jul 9. PMID:20693687 doi:10.1107/S0907444910020081
