Dedicator of cytokinesis protein
From Proteopedia
(Difference between revisions)
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- | <StructureSection load='2wmn' size='450' side='right' caption='Human dedicator of cytokinesis protein 9 DHR-2 domain (deepskyblue, lightsteelblue) complex with Cdc42 (green, seagreen) and GDP (PDB code [[2wmn]])' scene='75/752233/Cv/2'> | + | <StructureSection load='2wmn' size='450' side='right' caption='Human dedicator of cytokinesis protein 9 DHR-2 domain (deepskyblue, lightsteelblue) complex with Cdc42 (green, seagreen) and GDP (PDB code [[2wmn]])' scene='75/752233/Cv/2' pspeed='8'> |
== Function == | == Function == | ||
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== Structural highlights == | == Structural highlights == | ||
- | GDP interacts with Cdc42. DOCK9 has extensive contacts with Cdc42<ref>PMID:19745154</ref>. | + | <scene name='75/752233/Cv/4'>GDP interacts with Cdc42</scene>. DOCK9 has extensive contacts with Cdc42<ref>PMID:19745154</ref>. |
</StructureSection> | </StructureSection> |
Revision as of 12:14, 6 March 2017
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3D structures of dedicator of cytokinesis protein
Updated on 06-March-2017
References
- ↑ Su HC. Dedicator of cytokinesis 8 (DOCK8) deficiency. Curr Opin Allergy Clin Immunol. 2010 Dec;10(6):515-20. doi:, 10.1097/ACI.0b013e32833fd718. PMID:20864884 doi:http://dx.doi.org/10.1097/ACI.0b013e32833fd718
- ↑ Yang J, Zhang Z, Roe SM, Marshall CJ, Barford D. Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor. Science. 2009 Sep 11;325(5946):1398-402. PMID:19745154 doi:325/5946/1398