Antibody 3D structures
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | |||
== 3D Structures of Immunoglobulin == | == 3D Structures of Immunoglobulin == | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | Humanized mouse antibody (hmFab) is a modified mFab which resembles more hFab. | + | '''Humanized mouse antibody (hmFab)''' is a modified mFab which resembles more hFab.<br /> |
| + | '''Broadly neutralizing Fab''' and '''Neutralizing Fab''' are anti-HIV Fab. | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
*Fab | *Fab | ||
| - | **[[7fab]], [[1mco]], [[3na9]], [[3lrs]], [[3mme]], [[3hi5]], [[1vge]], [[3nfs]], [[1ad0]], [[3w9d]], [[4nm4]], [[8fab]], [[1opg]], [[4fnl]], [[4fqh]], [[1om3]], [[1aqk]], [[2hff]], [[2agj]], [[3hc0]], [[3g6a]], [[3dgg]], [[3dif]], [[1b2w]], [[3eyo]], [[3eyq]], [[2aj3]], [[3fzu]], [[3aaz]], [[3gje]] - hFab - human<br /> | + | **[[7fab]], [[1mco]], [[3na9]], [[3lrs]], [[3mme]], [[3hi5]], [[1vge]], [[3nfs]], [[1ad0]], [[3w9d]], [[4nm4]], [[8fab]], [[1opg]], [[4fnl]], [[4fqh]], [[1om3]], [[1aqk]], [[2hff]], [[2agj]], [[3hc0]], [[3g6a]], [[3dgg]], [[3dif]], [[1b2w]], [[3eyo]], [[3eyq]], [[2aj3]], [[3fzu]], [[3aaz]], [[3gje]], [[5fhb]], [[5fha]], [[5f6i]], [[5f6h]], [[5drw]], [[5d6c]], [[4py7]], [[4ptt]], [[4ob5]] - hFab - human<br /> |
**[[3naa]], [[3nab]], [[3nac]], [[3ncj]], [[3o2v]], [[3hc3]], [[3hc4]] - hFab (mutant)<br /> | **[[3naa]], [[3nab]], [[3nac]], [[3ncj]], [[3o2v]], [[3hc3]], [[3hc4]] - hFab (mutant)<br /> | ||
| - | **[[3i75]], [[1nqb]], [[1f4w]], [[1aif]], [[1ghf]], [[2z91]], [[1ind]], [[3bkc]], [[3bkm]], [[1iy0]], [[3pp3]], [[3pp4]], [[3okm]], [[6fab]], 2hkh]], [[1ay1]], [[1nbv]], [[1qbm]], [[1bbd]], [[1dsf]], [[1gpo]], [[1mnu]], [[1igf]], [[1for]], [[1k6q]], [[1bz7]], [[1dqd]], [[2ipt]], [[2iq9]], [[2iqa]], [[2w60]], [[2w9d]], [[3iu4]], [[1q9k]], [[1q9l]], [[1q9o]], [[2z4q]], [[1cl7]], [[1n4x]], [[1cr9]], [[1r24]], [[1gig]], [[1uyw]], [[1cgs]], [[2cgr]], [[1q0x]], [[1ibg]], [[3eo0]], [[2op4]], [[2q76]], [[2ojz]], [[2g60]], [[2dbl]], [[1dbj]], [[1dbk]], [[1dbm]], [[1dba]], [[1mrc]], [[2gcy]], [[1flr]], [[1uz6]], [[1rfd]], [[1t2q]], [[1ggb]], [[1ggc]], [[1bm3]], [[2eh7]], [[2fat]], [[3cfc]], [[1fl3]], [[3cfe]], [[4j1u]], [[4gq9]], [[3qg7]], [[3rvt]], [[3s62]], [[4gay]] - mFab – mouse<br /> | + | **[[3i75]], [[1nqb]], [[1f4w]], [[1aif]], [[1ghf]], [[2z91]], [[1ind]], [[3bkc]], [[3bkm]], [[1iy0]], [[3pp3]], [[3pp4]], [[3okm]], [[6fab]], 2hkh]], [[1ay1]], [[1nbv]], [[1qbm]], [[1bbd]], [[1dsf]], [[1gpo]], [[1mnu]], [[1igf]], [[1for]], [[1k6q]], [[1bz7]], [[1dqd]], [[2ipt]], [[2iq9]], [[2iqa]], [[2w60]], [[2w9d]], [[3iu4]], [[1q9k]], [[1q9l]], [[1q9o]], [[2z4q]], [[1cl7]], [[1n4x]], [[1cr9]], [[1r24]], [[1gig]], [[1uyw]], [[1cgs]], [[2cgr]], [[1q0x]], [[1ibg]], [[3eo0]], [[2op4]], [[2q76]], [[2ojz]], [[2g60]], [[2dbl]], [[1dbj]], [[1dbk]], [[1dbm]], [[1dba]], [[1mrc]], [[2gcy]], [[1flr]], [[1uz6]], [[1rfd]], [[1t2q]], [[1ggb]], [[1ggc]], [[1bm3]], [[2eh7]], [[2fat]], [[3cfc]], [[1fl3]], [[3cfe]], [[4j1u]], [[4gq9]], [[3qg7]], [[3rvt]], [[3s62]], [[4gay]], [[5mx3]], [[5l88]], [[5i66]], [[5cma]], [[5az2]], [[4z0b]], [[4qth]], [[4poz]] - mFab – mouse<br /> |
**[[3eot]], [[2d03]], [[3esv]], [[3et9]] – mFab (mutant)<br /> | **[[3eot]], [[2d03]], [[3esv]], [[3et9]] – mFab (mutant)<br /> | ||
**[[3iy2]], [[3iy3]], [[3iy4]], [[3iy5]], [[3iy6]], [[3iy7]] - mFab – Cryo EM<br /> | **[[3iy2]], [[3iy3]], [[3iy4]], [[3iy5]], [[3iy6]], [[3iy7]] - mFab – Cryo EM<br /> | ||
| Line 17: | Line 17: | ||
**[[1cqk]] – mFab MAK33 CH3 domain<br /> | **[[1cqk]] – mFab MAK33 CH3 domain<br /> | ||
**[[3mj8]], [[3r06]] – AhFab – Armenian hamster<br /> | **[[3mj8]], [[3r06]] – AhFab – Armenian hamster<br /> | ||
| - | **[[3iy1]], [[1zan]] – | + | **[[3iy1]], [[1zan]] – raFab – rat<br /> |
**[[4k3e]], [[4k3d]] – bFab – bovine<br /> | **[[4k3e]], [[4k3d]] – bFab – bovine<br /> | ||
| - | **[[4b41]], [[1shm]], [[2xa3]] – LgFab – ''Lama glama''<br /> | + | **[[4b41]], [[1shm]], [[2xa3]], [[5sv4]], [[4w81]], [[4w70]], [[4w68]], [[4tyu]], [[4m3j]] – LgFab – ''Lama glama''<br /> |
| + | **[[4u05]] – LgFab (mutant)<br /> | ||
**[[1f2x]] – cFab – camel<br /> | **[[1f2x]] – cFab – camel<br /> | ||
| + | **[[4u05]] – LgFab (mutant)<br /> | ||
*Anti-HIV Fab | *Anti-HIV Fab | ||
| - | **[[1rz7]], [[1rz8]], [[1rzf]], [[1rzg]], [[1rzi]], [[3mlj]], [[3mug]], [[3juy]], [[3qeh]], [[3ttn]], [[rpi]], [[3tnm]], [[4fz8]], [[4f58]], [[4f57]], [[4f5a]] - hFab <br /> | + | **[[1rz7]], [[1rz8]], [[1rzf]], [[1rzg]], [[1rzi]], [[3mlj]], [[3mug]], [[3juy]], [[3qeh]], [[3ttn]], [[rpi]], [[3tnm]], [[4fz8]], [[4f58]], [[4f57]], [[4f5a]], [[5iie]], [[5dt1]], [[5cey]], [[5cex]], [[5cck]], [[5bzw]], [[5bzd]], [[4ut7]], [[4rqq]] - hFab <br /> |
**[[3nz8]], [[3o6k]], [[3ntc]], [[3qeg]] – mFab <br /> | **[[3nz8]], [[3o6k]], [[3ntc]], [[3qeg]] – mFab <br /> | ||
| + | **[[5kg9]] – hmFab RE505-22<br /> | ||
| + | **[[5dd6]], [[5dd5]], [[5dd3]], [[5dd1]], [[4rfe]], [[4q2z]] – rmFab – rhesus macaque <br /> | ||
*Fab: small molecule complex | *Fab: small molecule complex | ||
**[[3o2w]] - hFab 1e9 (mutant) + transition state analog<br /> | **[[3o2w]] - hFab 1e9 (mutant) + transition state analog<br /> | ||
| - | **[[3ra7]] – mFab + digoxigenin | + | **[[3ra7]] – mFab + digoxigenin <br /> |
**[[3okd]], [[3oke]], [[3okk]], [[3okl]], [[3okn]], [[3oko]], [[3hzk]], [[3hzm]], [[3hzv]], [[3hzy]], [[3pho]], [[3phq]], [[3hns]], [[3hnt]], [[3hnv]] - mFab + liposaccharide<br /> | **[[3okd]], [[3oke]], [[3okk]], [[3okl]], [[3okn]], [[3oko]], [[3hzk]], [[3hzm]], [[3hzv]], [[3hzy]], [[3pho]], [[3phq]], [[3hns]], [[3hnt]], [[3hnv]] - mFab + liposaccharide<br /> | ||
**[[3oau]] – hFab 2g12 (mutant) + mannose<br /> | **[[3oau]] – hFab 2g12 (mutant) + mannose<br /> | ||
| + | **[[4ptu]] – hFab + rhamnose<br /> | ||
**[[1ikf]] – hFab R45 + cyclosporin<br /> | **[[1ikf]] – hFab R45 + cyclosporin<br /> | ||
**[[3oay]], [[3oaz]], [[3ob0]], [[1zls]], [[1zlu]], [[1zlv]], [[1zlw]] - hFab 2g12 + glycan<br /> | **[[3oay]], [[3oaz]], [[3ob0]], [[1zls]], [[1zlu]], [[1zlv]], [[1zlw]] - hFab 2g12 + glycan<br /> | ||
| - | **[[2jb5]], [[2jb6]] - | + | **[[2jb5]], [[2jb6]] - hmFab + hapten<br /> |
**[[1ine]], [[1ub5]], [[1ub6]] - mFab + hapten<br /> | **[[1ine]], [[1ub5]], [[1ub6]] - mFab + hapten<br /> | ||
**[[3ls4]] – mFab + tetrahydrocannabinol<br /> | **[[3ls4]] – mFab + tetrahydrocannabinol<br /> | ||
**[[1mfc]], [[1mfd]], [[1mfe]], [[4hgw]] – mFab + polysaccharide<br /> | **[[1mfc]], [[1mfd]], [[1mfe]], [[4hgw]] – mFab + polysaccharide<br /> | ||
| - | **[[1op3]], [[1op5]] - hFab + polysaccharide<br /> | + | **[[1op3]], [[1op5]], [[5i8o]] - hFab + polysaccharide<br /> |
| - | **[[3eyv]] - | + | **[[3eyv]] - hmFab 13G5 (mutant) + hapten<br /> |
**[[2ntf]] - mFab RS2-1G9 + lactone analog<br /> | **[[2ntf]] - mFab RS2-1G9 + lactone analog<br /> | ||
**[[1riu]], [[1riv]], [[1qyg]], [[1q72]] - mFab + cocaine derivative<br /> | **[[1riu]], [[1riv]], [[1qyg]], [[1q72]] - mFab + cocaine derivative<br /> | ||
| Line 70: | Line 75: | ||
**[[3h0t]] - hFab + hepcidin peptide<br /> | **[[3h0t]] - hFab + hepcidin peptide<br /> | ||
**[[1sm3]] - hFab SM3 + peptide<br /> | **[[1sm3]] - hFab SM3 + peptide<br /> | ||
| + | **[[4why]], [[4wht]] - hFab anti-HIV + peptide<br /> | ||
| + | **[[5ea0]] - hFab 7968 + complement factor peptide<br /> | ||
| + | **[[4z0x]], [[4xvj]] - hFab + HCV E2 peptide<br /> | ||
**[[3eyf]] – hFab + cytomegalovirus peptide<br /> | **[[3eyf]] – hFab + cytomegalovirus peptide<br /> | ||
**[[2hfg]], [[2h9g]] – hFab + TNF receptor peptide<br /> | **[[2hfg]], [[2h9g]] – hFab + TNF receptor peptide<br /> | ||
| Line 86: | Line 94: | ||
**[[1frg]], [[1him]], [[1hin]], [[1ifh]] - mFab + hemagglutinin peptide<br /> | **[[1frg]], [[1him]], [[1hin]], [[1ifh]] - mFab + hemagglutinin peptide<br /> | ||
**[[1tet]] – mFab + cholera toxin peptide<br /> | **[[1tet]] – mFab + cholera toxin peptide<br /> | ||
| + | **[[5epm]] – mFab + therapotoxin peptide<br /> | ||
| + | **[[5eor]], [[5eoq]] – mFab + protein A27 peptide<br /> | ||
**[[1i8i]], [[1i8k]] – mFab + EGFR peptide<br /> | **[[1i8i]], [[1i8k]] – mFab + EGFR peptide<br /> | ||
**[[1i8k]] – mFab + EGFR peptide<br /> | **[[1i8k]] – mFab + EGFR peptide<br /> | ||
| Line 91: | Line 101: | ||
**[[1i8k]] – mFab + EGFR peptide<br /> | **[[1i8k]] – mFab + EGFR peptide<br /> | ||
**[[4gag]], [[4gaj]] – mFab + genome polyprotein peptide<br /> | **[[4gag]], [[4gaj]] – mFab + genome polyprotein peptide<br /> | ||
| - | **[[3bky]] – | + | **[[3bky]] – hmFab + CD20 peptide<br /> |
**[[4hs8]] – hFab + hepatitis virus peptide <br /> | **[[4hs8]] – hFab + hepatitis virus peptide <br /> | ||
| + | **[[5dmg]] – rFab + microtubule-associated protein peptide - rabbit<br /> | ||
| + | **[[5dd0]] – rmFab + peptide<br /> | ||
*Anti-HIV Fab: peptide complex | *Anti-HIV Fab: peptide complex | ||
| - | **[[3egs]], [[3drt]], [[3drq]], [[3dro]], [[2fx7]], [[2fx8]], [[2fx9]], [[2cmr]], [[1tzg]], [[1tjg]], [[3mnw]], [[3moa]], [[3mob]], [[3mod]], [[1tjh]], [[1tji]], [[1u8h]], [[1u8i]], [[1u8j]], [[1u8k]], [[1u8l]], [[1u8m]], [[1u8n]], [[1u8o]], [[1u8p]], [[1u8q]], [[1u91]], [[1u92]], [[1u93]], [[1u95]], [[2f5b]] - hFab anti-HIV + gp41 peptide<br /> | + | **[[3egs]], [[3drt]], [[3drq]], [[3dro]], [[2fx7]], [[2fx8]], [[2fx9]], [[2cmr]], [[1tzg]], [[1tjg]], [[3mnw]], [[3moa]], [[3mob]], [[3mod]], [[1tjh]], [[1tji]], [[1u8h]], [[1u8i]], [[1u8j]], [[1u8k]], [[1u8l]], [[1u8m]], [[1u8n]], [[1u8o]], [[1u8p]], [[1u8q]], [[1u91]], [[1u92]], [[1u93]], [[1u95]], [[2f5b]], [[3go1]], [[5drz]], [[4ydv]] - hFab anti-HIV + gp41 peptide<br /> |
**[[3ghb]], [[3ghe]], [[3c2a]] - hFab anti-HIV + envelope glycoprotein peptide<br /> | **[[3ghb]], [[3ghe]], [[3c2a]] - hFab anti-HIV + envelope glycoprotein peptide<br /> | ||
| - | **[[3go1]] - hFab anti-HIV + envelope glycoprotein gp160 peptide<br /> | ||
**[[3fn0]], [[2oqj]] - hFab + peptide<br /> | **[[3fn0]], [[2oqj]] - hFab + peptide<br /> | ||
**[[2b0s]], [[2b1a]], [[2b1h]], [[3se8]], [[3se9]], [[4jkp]], [[4jpv]], [[4jb9]] - hFab anti-HIV + glycoprotein gp120 peptide<br /> | **[[2b0s]], [[2b1a]], [[2b1h]], [[3se8]], [[3se9]], [[4jkp]], [[4jpv]], [[4jb9]] - hFab anti-HIV + glycoprotein gp120 peptide<br /> | ||
| Line 110: | Line 121: | ||
**[[3raj]] – mFab HB7 + CD38<br /> | **[[3raj]] – mFab HB7 + CD38<br /> | ||
**[[3o0r]] – mFab + nitric oxide reductase<br /> | **[[3o0r]] – mFab + nitric oxide reductase<br /> | ||
| - | **[[3mac]], [[3ma9]] – hFab | + | **[[3mac]], [[3ma9]] – hFab anti-HIV 8062 + transmembrane glycoprotein<br /> |
| + | **[[4xak]] – hFab anti-HIV M336 + spike glycoprotein<br /> | ||
**[[3pnw]] – hFab + Tudor domain-containing protein 3<br /> | **[[3pnw]] – hFab + Tudor domain-containing protein 3<br /> | ||
**[[3h42]] - hFab LDLR + proprotein convertase subtilisin/kexin<br /> | **[[3h42]] - hFab LDLR + proprotein convertase subtilisin/kexin<br /> | ||
**[[3nh7]] – hFab ABD1556 + bone morphogenetic protein receptor<br /> | **[[3nh7]] – hFab ABD1556 + bone morphogenetic protein receptor<br /> | ||
**[[3hi6]] – hFab AL-57 + integrin<br /> | **[[3hi6]] – hFab AL-57 + integrin<br /> | ||
| - | **[[2vxs]] - hFab + interleukin<br /> | + | **[[2vxs]], [[5fhx]] - hFab + interleukin<br /> |
**[[3b2u]], [[3b2v]] – hFab IMC-11F8 + EGFR<br /> | **[[3b2u]], [[3b2v]] – hFab IMC-11F8 + EGFR<br /> | ||
**[[2r0k]], [[2r0l]] – hFab + HGFA<br /> | **[[2r0k]], [[2r0l]] – hFab + HGFA<br /> | ||
| Line 122: | Line 134: | ||
**[[3kr3]] – hFab + IGF-II<br /> | **[[3kr3]] – hFab + IGF-II<br /> | ||
**[[3g6d]] – hFab CNTO607 + IL-13<br /> | **[[3g6d]] – hFab CNTO607 + IL-13<br /> | ||
| - | **[[3idx]], [[3idy]], [[2ny7]], [[4jpw]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lss]], [[4lst]], [[4lsu]], [[4lsv]] - hFab + gp120 core<br /> | + | **[[3idx]], [[3idy]], [[2ny7]], [[4jpw]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lss]], [[4lst]], [[4lsu]], [[4lsv]], [[5te4]], [[5fyl]], [[5f9w]], [[5f96]], [[5f6j]], [[4ywg]], [[4ye4]], [[4ydl]], [[4ydk]], [[4ydj]], [[4ydi]], [[4yc2]], [[4ybl]], [[4s1s]], [[4s1r]], [[4s1q]], [[4rwy]], [[4rfn]] - hFab anti-HIV + gp120 core<br /> |
| - | **[[2x7l]] – | + | **[[4xnz]], [[4xny]], [[4xmp]] - hFab anti-HIV + gp41<br /> |
| - | **[[3gbm]], [[3gbn]], [[3lzf]], [[3fku]], [[3sdy]], [[3ztj]], [[3ztn]], [[4fp8]], [[4fqi]], [[4fqj]], [[4fqk]], [[4fql]], [[4fqr]], [[4fqv]], [[4fqy]], [[4gxu]], [[4nm8]]- hFab + hemagglutinin<br /> | + | **[[2x7l]], [[5dhz]], [[5dhy]], [[5dhx]], [[5dhv]] – hFab anti-HIV + HIV REV<br /> |
| + | **[[3gbm]], [[3gbn]], [[3lzf]], [[3fku]], [[3sdy]], [[3ztj]], [[3ztn]], [[4fp8]], [[4fqi]], [[4fqj]], [[4fqk]], [[4fql]], [[4fqr]], [[4fqv]], [[4fqy]], [[4gxu]], [[4nm8]], [[5gjt]], [[5gjs]], [[5dur]], [[5c0s]], [[4yk4]], [[4py8]] - hFab + hemagglutinin<br /> | ||
| + | **[[4r8w]] - hFab anti-HIV + hemagglutinin<br /> | ||
**[[3g6j]] – hFab + complement C3<br /> | **[[3g6j]] – hFab + complement C3<br /> | ||
**[[1fsk]] - mFab + pollen allergen<br /> | **[[1fsk]] - mFab + pollen allergen<br /> | ||
| Line 143: | Line 157: | ||
**[[3skj]] – hFab + ephrin receptor<br /> | **[[3skj]] – hFab + ephrin receptor<br /> | ||
**[[3sob]] – hFab + LPR6<br /> | **[[3sob]] – hFab + LPR6<br /> | ||
| + | **[[5lcv]] – hFab + polyprotein<br /> | ||
| + | **[[5gzo]], [[5gzn]] – hFab + zika polyprotein<br /> | ||
| + | **[[5lbs]] – hFab + envelope protein<br /> | ||
| + | **[[4utb]], [[4uta]], [[4ut9]], [[4ut6]] – hFab anti-HIV + dengue envelope protein<br /> | ||
| + | **[[5hj3]], [[5fhc]] – hFab + ebola envelope protein<br /> | ||
| + | **[[5kn5]] - hFab + protransforming growth factor alpha<br /> | ||
| + | **[[5c8j]] – hFab + protein MJ0480<br /> | ||
| + | **[[4zso]] – hFab + natural cytotoxicity triggering receptor<br /> | ||
| + | **[[5f3h]], [[5f3b]] - hmFab + growth factor 8<br /> | ||
| + | **[[4v1d]] - hFab + mammal toxin CN2 <br /> | ||
| + | **[[4rrp]] - hFab + ASF1P <br /> | ||
| + | **[[4qci]] - hFab + platelet factor B<br /> | ||
| + | **[[4mxv]] - hFab + TNFR-III <br /> | ||
**[[3vg9]] – hFab + adenosine receptor<br /> | **[[3vg9]] – hFab + adenosine receptor<br /> | ||
**[[3vga]] – hFab + adenosine receptor (mutant)<br /> | **[[3vga]] – hFab + adenosine receptor (mutant)<br /> | ||
| Line 162: | Line 189: | ||
**[[1qfw]] – mFab + gonadotropin<br /> | **[[1qfw]] – mFab + gonadotropin<br /> | ||
**[[4cad]] – mFab + RCE1<br /> | **[[4cad]] – mFab + RCE1<br /> | ||
| - | **[[4m48]] – mFab + dopamine transporter<br /> | + | **[[4m48]], [[4xpt]], [[4xph]], [[4xpg]], [[4xpf]], [[4xpb]], [[4xpa]], [[4xp9]], [[4xp6]], [[4xp5]], [[4xp4]], [[4xp1]], [[4xnx]], [[4xnu]] – mFab + dopamine transporter<br /> |
| + | **[[5i75]], [[5i74]], [[5i73]], [[5i71]], [[5i6z]], [[5i6x]] – mFab + serotonin transporter<br /> | ||
**[[1yjd]] – mFab 5.11A1 + CD28<br /> | **[[1yjd]] – mFab 5.11A1 + CD28<br /> | ||
**[[1sy6]] – mFab OKT3 + CD3<br /> | **[[1sy6]] – mFab OKT3 + CD3<br /> | ||
| + | **[[5dfv]] – mFab + CD81<br /> | ||
| + | **[[4r0l]] – mFab + CD28<br /> | ||
**[[4qex]], [[4k2u]] – mFab + erythrocyte binding antigen<br /> | **[[4qex]], [[4k2u]] – mFab + erythrocyte binding antigen<br /> | ||
**[[1afv]] – mFab anti-HIV + capsid protein C<br /> | **[[1afv]] – mFab anti-HIV + capsid protein C<br /> | ||
| Line 172: | Line 202: | ||
**[[2r9h]] – mFab + exchange transporter ClCA<br /> | **[[2r9h]] – mFab + exchange transporter ClCA<br /> | ||
**[[1nca]], [[1ncb]], [[1ncc]], [[1ncd]] – mFab + neuraminidase<br /> | **[[1nca]], [[1ncb]], [[1ncc]], [[1ncd]] – mFab + neuraminidase<br /> | ||
| + | **[[4qnp]] – mFab anti-HIV + neuraminidase<br /> | ||
**[[1rjl]] – mFab + outer surface protein<br /> | **[[1rjl]] – mFab + outer surface protein<br /> | ||
**[[1mhh]] – mFab + protein L (mutant)<br /> | **[[1mhh]] – mFab + protein L (mutant)<br /> | ||
| Line 188: | Line 219: | ||
**[[3ab0]] – mFab + BCLA protein<br /> | **[[3ab0]] – mFab + BCLA protein<br /> | ||
**[[3etb]] – mFab M18 (mutant) + anthrax-protective antigen<br /> | **[[3etb]] – mFab M18 (mutant) + anthrax-protective antigen<br /> | ||
| - | **[[3f5w]], [[3pjs]], [[3efd]], [[3eff]], [[2hjf]], [[2w0f]], [[4msw]] – mFab + KcsA K+ channel<br /> | + | **[[3f5w]], [[3pjs]], [[3efd]], [[3eff]], [[2hjf]], [[2w0f]], [[4msw]], [[4uuj]] – mFab + KcsA K+ channel<br /> |
| - | **[[3stl]], [[3stz]], [[4i9w]] - mFab + KcsA K+ channel (mutant)<br /> | + | **[[3stl]], [[3stz]], [[4i9w]], [[5ec2]], [[5ec1]], [[5ebw]], [[5ebm]], [[5ebl]], [[5e1a]] - mFab + KcsA K+ channel (mutant)<br /> |
**[[1kb5]] – mFab + T-cell receptor<br /> | **[[1kb5]] – mFab + T-cell receptor<br /> | ||
**[[4i18]] – mFab + pro-lactin receptor<br /> | **[[4i18]] – mFab + pro-lactin receptor<br /> | ||
**[[1uwx]] – mFab + protein G prime <br /> | **[[1uwx]] – mFab + protein G prime <br /> | ||
**[[4ckd]] – mFab + β-galactosidase <br /> | **[[4ckd]] – mFab + β-galactosidase <br /> | ||
| + | **[[5tih]] – mFab + cysteine-rich protective antigen<br /> | ||
| + | **[[5t5n]], [[4rdq]] – mFab + bestrophin <br /> | ||
| + | **[[5e94]] – mFab + glucagon-like receptor <br /> | ||
| + | **[[5e8d]] – mFab + proepiregulin <br /> | ||
| + | **[[5kvg]], [[5kvf]], [[5kve]], [[5kvd]], [[5jhl]] – mFab + zika envelope DIII <br /> | ||
| + | **[[5jym]] – mFab + cadherin<br /> | ||
| + | **[[5fb8]] - mFab + interleukin<br /> | ||
| + | **[[5d96]], [[5d93]] - mFab + sulfhydryl oxidase<br /> | ||
| + | **[[4ybq]] – mFab + fructose transporter<br /> | ||
| + | **[[4xzu]] - mFab + coagulation factor <br /> | ||
| + | **[[4u6h]] - mFab + virion membrane protein M25 <br /> | ||
| + | **[[4r9y]], [[4r97]] - mFab + platelet factor 4<br /> | ||
| + | **[[4qww]] - mFab + acetylcholinesterase <br /> | ||
| + | **[[4qti]] – mFab + urokinase-type plasminogen activator <br /> | ||
| + | **[[4pp2]] – mFab + peptidase<br /> | ||
| + | **[[4p3d]], [[4p3c]] – mFab + metalloproteinase 14<br /> | ||
| + | **[[4ong]], [[4onf]] - mFab + amyloid-β A4 protein<br /> | ||
| + | **[[4oii]] - mFab + NS1<br /> | ||
**[[3fmg]] – mFab + glycoprotein VP7<br /> | **[[3fmg]] – mFab + glycoprotein VP7<br /> | ||
**[[3ve0]] - mFab + Ebola envelope glycoprotein<br /> | **[[3ve0]] - mFab + Ebola envelope glycoprotein<br /> | ||
| - | **[[3k7u]], [[3k80]] – LgFab + MP18 RNA editing protein | + | **[[3k7u]], [[3k80]] – LgFab + MP18 RNA editing protein <br /> |
**[[3mj9]] – AhFab HL4E10 + JAML <br /> | **[[3mj9]] – AhFab HL4E10 + JAML <br /> | ||
**[[3r08]] - AhFab 2C11 + CD3ε<br /> | **[[3r08]] - AhFab 2C11 + CD3ε<br /> | ||
| Line 205: | Line 254: | ||
**[[3k81]], [[3stb]], [[4dk3]], [[4dk6]], [[4dka]] – LgFab + RNA editing complex protein<br /> | **[[3k81]], [[3stb]], [[4dk3]], [[4dk6]], [[4dka]] – LgFab + RNA editing complex protein<br /> | ||
**[[3p0g]], [[4lde]], [[4ldl]], [[4ldo]] – LgFab + adrenergic receptor<br /> | **[[3p0g]], [[4lde]], [[4ldl]], [[4ldo]] – LgFab + adrenergic receptor<br /> | ||
| + | **[[5tok]], [[5toj]] – LgFab + F glycoprotein<br /> | ||
| + | **[[5sv3]], [[5boz]] – LgFab + ricin<br /> | ||
| + | **[[5hm1]] – LgFab + gp41<br /> | ||
| + | **[[4n1h]], [[4m3k]] – LgFab + beta-lactamase<br /> | ||
| + | **[[5m95]], [[5m94]], [[4wgw]], [[4wgv]] – LgFab + metal cation transporter<br /> | ||
| + | **[[5hgg]] – Fab + urokinase-type plasminogen activator - Vicugna<br /> | ||
**[[1jto]], [[1jtp]], [[1jtt]], [[1ri8]], [[1xfp]], [[1zmy]], [[1zv5]], [[1zvh]] – cFab + lysozyme<br /> | **[[1jto]], [[1jtp]], [[1jtt]], [[1ri8]], [[1xfp]], [[1zmy]], [[1zv5]], [[1zvh]] – cFab + lysozyme<br /> | ||
**[[2x89]] – cFab + β-2-microglobulin<br /> | **[[2x89]] – cFab + β-2-microglobulin<br /> | ||
**[[4i0c]] – cFab + lysozyme<br /> | **[[4i0c]] – cFab + lysozyme<br /> | ||
| - | **[[4ht1]] – | + | **[[4ht1]] – rFab + TNF ligand 12 <br /> |
| + | **[[4n9g]] - rmFab + scaffold<br /> | ||
| - | *Fab: protein | + | *Fab: protein higher complexes |
**[[3ixx]], [[3ixy]] - mFab E53 + envelope glycoprotein + West Nile virus peptide<br /> | **[[3ixx]], [[3ixy]] - mFab E53 + envelope glycoprotein + West Nile virus peptide<br /> | ||
| - | **[[1g9m]], [[1g9n]], [[1gc1]], [[2i5y]], [[2i60]], [[2nxy]], [[2nxz]], [[2ny0]], [[2ny1]], [[2ny2]], [[2ny3]], [[2ny4]], [[2ny5]], [[2ny6]], [[3jwd]], [[3jwo]] | + | **[[1g9m]], [[1g9n]], [[1gc1]], [[2i5y]], [[2i60]], [[2nxy]], [[2nxz]], [[2ny0]], [[2ny1]], [[2ny2]], [[2ny3]], [[2ny4]], [[2ny5]], [[2ny6]], [[3jwd]], [[3jwo]], [[5a8h]], [[5a7x]], [[4r4h]] - hFab anti-HIV + envelope glycoprotein gp120 + CD4<br /> |
| + | **[[5jsa]], [[5js9]], [[5c7k]] - hFab anti-HIV + envelope glycoprotein gp120 + gp41<br /> | ||
| + | **[[4r4n]], [[4r4f]] - hFab anti-HIV + envelope glycoprotein gp120 + M48U1 peptide<br /> | ||
**[[2wuc]] - hFab 40 + hepatocyte growth factor activator + inhibitor<br /> | **[[2wuc]] - hFab 40 + hepatocyte growth factor activator + inhibitor<br /> | ||
| - | **[[3lqa]], [[2qad]] - hFab anti-HIV + CD4 + | + | **[[3lqa]], [[2qad]] - hFab anti-HIV + CD4 + gp41<br /> |
**[[3d85]] - hFab 7G10 + IL-12 + IL-23<br /> | **[[3d85]] - hFab 7G10 + IL-12 + IL-23<br /> | ||
| + | **[[4xwo]] - hFab + ATPase GET3 + Sec22<br /> | ||
| + | **[[4xvu]] - hFab + ATPase GET3 + NYV1<br /> | ||
| + | **[[4xtr]] - hFab + ATPase GET3 + PEP12P peptide<br /> | ||
| + | **[[4xmn]] - hFab + Sec13 + Nup145 + Nup84 + Nup120 + Nup85<br /> | ||
| + | **[[4xmn]] - hFab + Sec13 + Nup145 + Nup84 + Nup120 + Nup85 + SEH1<br /> | ||
| + | **[[4mxw]] - hFab + TNFR-III + lymphotoxin<br /> | ||
**[[3bt2]] – hFab anti-UPAR + urokinase-type plasminogen activator + vitronectin<br /> | **[[3bt2]] – hFab anti-UPAR + urokinase-type plasminogen activator + vitronectin<br /> | ||
**[[3gjf]], [[3hae]] – hFab + β-2-microglobulin + MHC antigen + NYESO peptide<br /> | **[[3gjf]], [[3hae]] – hFab + β-2-microglobulin + MHC antigen + NYESO peptide<br /> | ||
| - | **[[3gb7]], [[2p7t]], [[2h8p]], [[2hfe]], [[2atk]] - mFab + KcsA K+ channel + ion<br /> | + | **[[3gb7]], [[2p7t]], [[2h8p]], [[2hfe]], [[2atk]], [[4wfh]], [[4wfg]], [[4wff]], [[4wfe]] - mFab + KcsA K+ channel + ion<br /> |
**[[3or6]], [[3or7]], [[3ogc]], [[3fb7]], [[3f7v]], [[3f7y]], [[3fb5]], [[3fb6]], [[3fb8]], [[3iga]], [[2itc]], [[2itd]], [[2nlj]], [[2bob]], [[2boc]], [[1s5h]], [[1r3i]], [[1r3j]], [[1r3k]], [[1r3l]], [[1k4c]], [[1k4d]], [[3hpl]] - mFab + KcsA K+ channel (mutant) + ion<br /> | **[[3or6]], [[3or7]], [[3ogc]], [[3fb7]], [[3f7v]], [[3f7y]], [[3fb5]], [[3fb6]], [[3fb8]], [[3iga]], [[2itc]], [[2itd]], [[2nlj]], [[2bob]], [[2boc]], [[1s5h]], [[1r3i]], [[1r3j]], [[1r3k]], [[1r3l]], [[1k4c]], [[1k4d]], [[3hpl]] - mFab + KcsA K+ channel (mutant) + ion<br /> | ||
**[[2fd6]] – mFab ATN-615 + urokinase-type plasminogen activator + urokinase plasminogen receptor<br /> | **[[2fd6]] – mFab ATN-615 + urokinase-type plasminogen activator + urokinase plasminogen receptor<br /> | ||
| Line 228: | Line 292: | ||
**[[3sn6]] – LgFab + adrenergic receptor + guanine nucleotide-binding protein<br /> | **[[3sn6]] – LgFab + adrenergic receptor + guanine nucleotide-binding protein<br /> | ||
**[[4laj]] - LgFab + envelope glycoprotein gp120 + CD4<br /> | **[[4laj]] - LgFab + envelope glycoprotein gp120 + CD4<br /> | ||
| + | **[[4orz]] – LgFab + tyrosine protein kinase HCK + NEF<br /> | ||
*Full Immunoglobulin | *Full Immunoglobulin | ||
| Line 254: | Line 319: | ||
**[[1kxq]] – cFv + α-amylase<br /> | **[[1kxq]] – cFv + α-amylase<br /> | ||
**[[1mel]], [[1rjc]], [[1zvy]] – cFv + lysozyme<br /> | **[[1mel]], [[1rjc]], [[1zvy]] – cFv + lysozyme<br /> | ||
| + | **[[4u3x]] – hFv + lysozyme<br /> | ||
}} | }} | ||
Revision as of 11:30, 7 March 2017
3D Structures of Immunoglobulin
Updated on 07-March-2017
Humanized mouse antibody (hmFab) is a modified mFab which resembles more hFab.
Broadly neutralizing Fab and Neutralizing Fab are anti-HIV Fab.
