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Antibody 3D structures

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Line 4: Line 4:
'''Humanized mouse antibody (hmFab)''' is a modified mFab which resembles more hFab.<br />
'''Humanized mouse antibody (hmFab)''' is a modified mFab which resembles more hFab.<br />
-
'''Broadly neutralizing Fab''' and '''Neutralizing Fab''' are anti-HIV Fab.
+
'''Broadly neutralizing Fab''' and '''Neutralizing Fab''' are anti-HIV Fab.<br />
 +
'''Lama antibodies''' or '''nanobodies''' are natural single-domain antibodies containing just the heavy chain.
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
Line 31: Line 32:
**[[5dd6]], [[5dd5]], [[5dd3]], [[5dd1]], [[4rfe]], [[4q2z]] – rmFab – rhesus macaque <br />
**[[5dd6]], [[5dd5]], [[5dd3]], [[5dd1]], [[4rfe]], [[4q2z]] – rmFab – rhesus macaque <br />
-
*Fab: small molecule complex
+
*Human Fab: small molecule complex
**[[3o2w]] - hFab 1e9 (mutant) + transition state analog<br />
**[[3o2w]] - hFab 1e9 (mutant) + transition state analog<br />
-
**[[3ra7]] – mFab + digoxigenin <br />
 
-
**[[3okd]], [[3oke]], [[3okk]], [[3okl]], [[3okn]], [[3oko]], [[3hzk]], [[3hzm]], [[3hzv]], [[3hzy]], [[3pho]], [[3phq]], [[3hns]], [[3hnt]], [[3hnv]] - mFab + liposaccharide<br />
 
**[[3oau]] – hFab 2g12 (mutant) + mannose<br />
**[[3oau]] – hFab 2g12 (mutant) + mannose<br />
**[[4ptu]] – hFab + rhamnose<br />
**[[4ptu]] – hFab + rhamnose<br />
**[[1ikf]] – hFab R45 + cyclosporin<br />
**[[1ikf]] – hFab R45 + cyclosporin<br />
**[[3oay]], [[3oaz]], [[3ob0]], [[1zls]], [[1zlu]], [[1zlv]], [[1zlw]] - hFab 2g12 + glycan<br />
**[[3oay]], [[3oaz]], [[3ob0]], [[1zls]], [[1zlu]], [[1zlv]], [[1zlw]] - hFab 2g12 + glycan<br />
-
**[[2jb5]], [[2jb6]] - hmFab + hapten<br />
+
**[[1op3]], [[1op5]], [[5i8o]] - hFab + polysaccharide<br />
 +
 
 +
*Mouse Fab: small molecule complex
 +
 
 +
**[[3ra7]] – mFab + digoxigenin <br />
 +
**[[3okd]], [[3oke]], [[3okk]], [[3okl]], [[3okn]], [[3oko]], [[3hzk]], [[3hzm]], [[3hzv]], [[3hzy]], [[3pho]], [[3phq]], [[3hns]], [[3hnt]], [[3hnv]] - mFab + liposaccharide<br />
**[[1ine]], [[1ub5]], [[1ub6]] - mFab + hapten<br />
**[[1ine]], [[1ub5]], [[1ub6]] - mFab + hapten<br />
**[[3ls4]] – mFab + tetrahydrocannabinol<br />
**[[3ls4]] – mFab + tetrahydrocannabinol<br />
**[[1mfc]], [[1mfd]], [[1mfe]], [[4hgw]] – mFab + polysaccharide<br />
**[[1mfc]], [[1mfd]], [[1mfe]], [[4hgw]] – mFab + polysaccharide<br />
-
**[[1op3]], [[1op5]], [[5i8o]] - hFab + polysaccharide<br />
 
-
**[[3eyv]] - hmFab 13G5 (mutant) + hapten<br />
 
**[[2ntf]] - mFab RS2-1G9 + lactone analog<br />
**[[2ntf]] - mFab RS2-1G9 + lactone analog<br />
**[[1riu]], [[1riv]], [[1qyg]], [[1q72]] - mFab + cocaine derivative<br />
**[[1riu]], [[1riv]], [[1qyg]], [[1q72]] - mFab + cocaine derivative<br />
Line 61: Line 63:
**[[1dl7]] - mFab MCPC603 + phosphocholine<br />
**[[1dl7]] - mFab MCPC603 + phosphocholine<br />
**[[3cfb]], [[3cfd]], [[2g2r]] – mFab + stilbene hapten<br />
**[[3cfb]], [[3cfd]], [[2g2r]] – mFab + stilbene hapten<br />
 +
 +
*Other Fab: small molecule complex
 +
 +
**[[2jb5]], [[2jb6]] - hmFab + hapten<br />
 +
**[[3eyv]] - hmFab 13G5 (mutant) + hapten<br />
**[[1i3u]], [[1i3v]] - LgFab + hapten<br />
**[[1i3u]], [[1i3v]] - LgFab + hapten<br />
-
*Fab: peptide complex
+
*Mouse Fab: peptide complex
**[[3e8u]] - mFab + BNP peptide<br />
**[[3e8u]] - mFab + BNP peptide<br />
Line 73: Line 80:
**[[2zpk]] – mFab + proteinase-activated receptor peptide<br />
**[[2zpk]] – mFab + proteinase-activated receptor peptide<br />
**[[3ifl]], [[3ifn]], [[3ifo]], [[3ifp]] - mFab + amyloid peptide<br />
**[[3ifl]], [[3ifn]], [[3ifo]], [[3ifp]] - mFab + amyloid peptide<br />
-
**[[3h0t]] - hFab + hepcidin peptide<br />
 
-
**[[1sm3]] - hFab SM3 + peptide<br />
 
-
**[[4why]], [[4wht]] - hFab anti-HIV + peptide<br />
 
-
**[[5ea0]] - hFab 7968 + complement factor peptide<br />
 
-
**[[4z0x]], [[4xvj]] - hFab + HCV E2 peptide<br />
 
-
**[[3eyf]] – hFab + cytomegalovirus peptide<br />
 
-
**[[2hfg]], [[2h9g]] – hFab + TNF receptor peptide<br />
 
-
**[[3csy]] - hFab + Ebola envelope glycoprotein peptide<br />
 
**[[2eh8]] - mFab + PRES1 peptide<br />
**[[2eh8]] - mFab + PRES1 peptide<br />
**[[2brr]] – mFab + outer membrane protein peptide<br />
**[[2brr]] – mFab + outer membrane protein peptide<br />
Line 91: Line 90:
**[[1mvu]] – mFab + glycoprotein <br />
**[[1mvu]] – mFab + glycoprotein <br />
**[[2ap2]] – mFab + glycoprotein peptide + C-myc peptide<br />
**[[2ap2]] – mFab + glycoprotein peptide + C-myc peptide<br />
-
**[[2hh0]] – hFab/mFab + prion protein peptide<br />
 
**[[1frg]], [[1him]], [[1hin]], [[1ifh]] - mFab + hemagglutinin peptide<br />
**[[1frg]], [[1him]], [[1hin]], [[1ifh]] - mFab + hemagglutinin peptide<br />
**[[1tet]] – mFab + cholera toxin peptide<br />
**[[1tet]] – mFab + cholera toxin peptide<br />
Line 101: Line 99:
**[[1i8k]] – mFab + EGFR peptide<br />
**[[1i8k]] – mFab + EGFR peptide<br />
**[[4gag]], [[4gaj]] – mFab + genome polyprotein peptide<br />
**[[4gag]], [[4gaj]] – mFab + genome polyprotein peptide<br />
-
**[[3bky]] – hmFab + CD20 peptide<br />
+
 
 +
*Human Fab: peptide complex
 +
 
 +
**[[3h0t]] - hFab + hepcidin peptide<br />
 +
**[[1sm3]] - hFab SM3 + peptide<br />
 +
**[[4why]], [[4wht]] - hFab anti-HIV + peptide<br />
 +
**[[5ea0]] - hFab 7968 + complement factor peptide<br />
 +
**[[4z0x]], [[4xvj]] - hFab + HCV E2 peptide<br />
 +
**[[3eyf]] – hFab + cytomegalovirus peptide<br />
 +
**[[2hfg]], [[2h9g]] – hFab + TNF receptor peptide<br />
 +
**[[3csy]] - hFab + Ebola envelope glycoprotein peptide<br />
**[[4hs8]] – hFab + hepatitis virus peptide <br />
**[[4hs8]] – hFab + hepatitis virus peptide <br />
 +
 +
*Other Fab: peptide complex
 +
 +
**[[2hh0]] – hmFab + prion protein peptide<br />
 +
**[[3bky]] – hmFab + CD20 peptide<br />
**[[5dmg]] – rFab + microtubule-associated protein peptide - rabbit<br />
**[[5dmg]] – rFab + microtubule-associated protein peptide - rabbit<br />
**[[5dd0]] – rmFab + peptide<br />
**[[5dd0]] – rmFab + peptide<br />
Line 117: Line 130:
**[[1svz]] - mFab anti-HIV + HIV-2 protease peptide<br />
**[[1svz]] - mFab anti-HIV + HIV-2 protease peptide<br />
-
*Fab: protein complex
+
*Human Fab: protein complex
-
**[[3raj]] – mFab HB7 + CD38<br />
 
-
**[[3o0r]] – mFab + nitric oxide reductase<br />
 
-
**[[3mac]], [[3ma9]] – hFab anti-HIV 8062 + transmembrane glycoprotein<br />
 
-
**[[4xak]] – hFab anti-HIV M336 + spike glycoprotein<br />
 
**[[3pnw]] – hFab + Tudor domain-containing protein 3<br />
**[[3pnw]] – hFab + Tudor domain-containing protein 3<br />
**[[3h42]] - hFab LDLR + proprotein convertase subtilisin/kexin<br />
**[[3h42]] - hFab LDLR + proprotein convertase subtilisin/kexin<br />
Line 130: Line 139:
**[[3b2u]], [[3b2v]] – hFab IMC-11F8 + EGFR<br />
**[[3b2u]], [[3b2v]] – hFab IMC-11F8 + EGFR<br />
**[[2r0k]], [[2r0l]] – hFab + HGFA<br />
**[[2r0k]], [[2r0l]] – hFab + HGFA<br />
-
**[[3ld8]], [[3ldb]] – AhFab + bifunctional arginine demethylase <br />
 
**[[3be1]], [[3n85]], [[1n8z]] - hFab + ERBB-2<br />
**[[3be1]], [[3n85]], [[1n8z]] - hFab + ERBB-2<br />
**[[3kr3]] – hFab + IGF-II<br />
**[[3kr3]] – hFab + IGF-II<br />
**[[3g6d]] – hFab CNTO607 + IL-13<br />
**[[3g6d]] – hFab CNTO607 + IL-13<br />
-
**[[3idx]], [[3idy]], [[2ny7]], [[4jpw]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lss]], [[4lst]], [[4lsu]], [[4lsv]], [[5te4]], [[5fyl]], [[5f9w]], [[5f96]], [[5f6j]], [[4ywg]], [[4ye4]], [[4ydl]], [[4ydk]], [[4ydj]], [[4ydi]], [[4yc2]], [[4ybl]], [[4s1s]], [[4s1r]], [[4s1q]], [[4rwy]], [[4rfn]] - hFab anti-HIV + gp120 core<br />
 
-
**[[4xnz]], [[4xny]], [[4xmp]] - hFab anti-HIV + gp41<br />
 
-
**[[2x7l]], [[5dhz]], [[5dhy]], [[5dhx]], [[5dhv]] – hFab anti-HIV + HIV REV<br />
 
**[[3gbm]], [[3gbn]], [[3lzf]], [[3fku]], [[3sdy]], [[3ztj]], [[3ztn]], [[4fp8]], [[4fqi]], [[4fqj]], [[4fqk]], [[4fql]], [[4fqr]], [[4fqv]], [[4fqy]], [[4gxu]], [[4nm8]], [[5gjt]], [[5gjs]], [[5dur]], [[5c0s]], [[4yk4]], [[4py8]] - hFab + hemagglutinin<br />
**[[3gbm]], [[3gbn]], [[3lzf]], [[3fku]], [[3sdy]], [[3ztj]], [[3ztn]], [[4fp8]], [[4fqi]], [[4fqj]], [[4fqk]], [[4fql]], [[4fqr]], [[4fqv]], [[4fqy]], [[4gxu]], [[4nm8]], [[5gjt]], [[5gjs]], [[5dur]], [[5c0s]], [[4yk4]], [[4py8]] - hFab + hemagglutinin<br />
-
**[[4r8w]] - hFab anti-HIV + hemagglutinin<br />
 
**[[3g6j]] – hFab + complement C3<br />
**[[3g6j]] – hFab + complement C3<br />
-
**[[1fsk]] - mFab + pollen allergen<br />
 
**[[2wub]], [[3k2u]] – hFab 40 + hepatocyte growth factor activator<br />
**[[2wub]], [[3k2u]] – hFab 40 + hepatocyte growth factor activator<br />
**[[3grw]] - hFab + fibroblast growth factor receptor<br />
**[[3grw]] - hFab + fibroblast growth factor receptor<br />
**[[3bdy]], [[2qr0]], [[2fjg]], [[2fjh]], [[1cz8]] – hFab + VEGF<br />
**[[3bdy]], [[2qr0]], [[2fjg]], [[2fjh]], [[1cz8]] – hFab + VEGF<br />
-
**[[1tzh]], [[1tzi]] - mFab + VEGF<br />
 
**[[3bqu]] – hFab 2F5 anti-HIV + mFab 3H6<br />
**[[3bqu]] – hFab 2F5 anti-HIV + mFab 3H6<br />
**[[1adq]] – hFab IGM + igG1 Fc<br />
**[[1adq]] – hFab IGM + igG1 Fc<br />
Line 160: Line 162:
**[[5gzo]], [[5gzn]] – hFab + zika polyprotein<br />
**[[5gzo]], [[5gzn]] – hFab + zika polyprotein<br />
**[[5lbs]] – hFab + envelope protein<br />
**[[5lbs]] – hFab + envelope protein<br />
-
**[[4utb]], [[4uta]], [[4ut9]], [[4ut6]] – hFab anti-HIV + dengue envelope protein<br />
 
**[[5hj3]], [[5fhc]] – hFab + ebola envelope protein<br />
**[[5hj3]], [[5fhc]] – hFab + ebola envelope protein<br />
**[[5kn5]] - hFab + protransforming growth factor alpha<br />
**[[5kn5]] - hFab + protransforming growth factor alpha<br />
**[[5c8j]] – hFab + protein MJ0480<br />
**[[5c8j]] – hFab + protein MJ0480<br />
**[[4zso]] – hFab + natural cytotoxicity triggering receptor<br />
**[[4zso]] – hFab + natural cytotoxicity triggering receptor<br />
-
**[[5f3h]], [[5f3b]] - hmFab + growth factor 8<br />
 
**[[4v1d]] - hFab + mammal toxin CN2 <br />
**[[4v1d]] - hFab + mammal toxin CN2 <br />
**[[4rrp]] - hFab + ASF1P <br />
**[[4rrp]] - hFab + ASF1P <br />
Line 174: Line 174:
**[[2qqk]], [[2qql]], [[2qqn]] – hFab + neuropilin<br />
**[[2qqk]], [[2qql]], [[2qqn]] – hFab + neuropilin<br />
**[[2vyr]] – hFab + MDM4<br />
**[[2vyr]] – hFab + MDM4<br />
-
**[[4c2i]] – hFab + dengue virus envelope protein<br />
+
**[[4c2i]] – hFab + dengue virus envelope protein - Cryo EM<br />
**[[4dag]] – hFab + metapneumovirus glycoprotein F0<br />
**[[4dag]] – hFab + metapneumovirus glycoprotein F0<br />
-
**[[1jps]] - hmFab D3H44 + tissue factor<br />
+
 
 +
*Mouse Fab: protein complex
 +
 
 +
**[[1tzh]], [[1tzi]] - mFab + VEGF<br />
 +
**[[1fsk]] - mFab + pollen allergen<br />
 +
**[[3raj]] – mFab HB7 + CD38<br />
 +
**[[3o0r]] – mFab + nitric oxide reductase<br />
**[[1ahw]] - mFab 5G9+ tissue factor<br />
**[[1ahw]] - mFab 5G9+ tissue factor<br />
**[[1eo8]], [[1ken]], [[4mhh]], [[4mhj]] - mFab + hemagglutinin<br />
**[[1eo8]], [[1ken]], [[4mhh]], [[4mhj]] - mFab + hemagglutinin<br />
Line 196: Line 202:
**[[4r0l]] – mFab + CD28<br />
**[[4r0l]] – mFab + CD28<br />
**[[4qex]], [[4k2u]] – mFab + erythrocyte binding antigen<br />
**[[4qex]], [[4k2u]] – mFab + erythrocyte binding antigen<br />
-
**[[1afv]] – mFab anti-HIV + capsid protein C<br />
 
-
**[[2b2x]] – rFab AQC2 + integrin<br />
 
-
**[[2r56]] – bFab igE + β-lactoglobulin <br />
 
-
**[[1bzq]], [[2p42]], [[2p43]], [[2p44]], [[2p45]], [[2p46]], [[2p47]], [[2p48]], [[2p49]], [[2p4a]] – bFab Cab-Rn05 + RNase<br />
 
**[[2r9h]] – mFab + exchange transporter ClCA<br />
**[[2r9h]] – mFab + exchange transporter ClCA<br />
**[[1nca]], [[1ncb]], [[1ncc]], [[1ncd]] – mFab + neuraminidase<br />
**[[1nca]], [[1ncb]], [[1ncc]], [[1ncd]] – mFab + neuraminidase<br />
-
**[[4qnp]] – mFab anti-HIV + neuraminidase<br />
 
**[[1rjl]] – mFab + outer surface protein<br />
**[[1rjl]] – mFab + outer surface protein<br />
**[[1mhh]] – mFab + protein L (mutant)<br />
**[[1mhh]] – mFab + protein L (mutant)<br />
**[[1pg7]] – mFab 6A6 + hmFab D3H44<br />
**[[1pg7]] – mFab 6A6 + hmFab D3H44<br />
-
**[[1pkq]] – hFab/mFab 8-18C5 + myelin glycoprotein<br />
 
**[[2jel]] – mFab JEL42 + histidine-containing protein<br />
**[[2jel]] – mFab JEL42 + histidine-containing protein<br />
**[[1nsn]] – mFab N10 + nuclease<br />
**[[1nsn]] – mFab N10 + nuclease<br />
Line 245: Line 245:
**[[3fmg]] – mFab + glycoprotein VP7<br />
**[[3fmg]] – mFab + glycoprotein VP7<br />
**[[3ve0]] - mFab + Ebola envelope glycoprotein<br />
**[[3ve0]] - mFab + Ebola envelope glycoprotein<br />
 +
 +
*Anti-HIV Fab: protein complex
 +
 +
**[[3mac]], [[3ma9]] – hFab anti-HIV 8062 + transmembrane glycoprotein<br />
 +
**[[4xak]] – hFab anti-HIV M336 + spike glycoprotein<br />
 +
**[[3idx]], [[3idy]], [[2ny7]], [[4jpw]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lss]], [[4lst]], [[4lsu]], [[4lsv]], [[5te4]], [[5fyl]], [[5f9w]], [[5f96]], [[5f6j]], [[4ywg]], [[4ye4]], [[4ydl]], [[4ydk]], [[4ydj]], [[4ydi]], [[4yc2]], [[4ybl]], [[4s1s]], [[4s1r]], [[4s1q]], [[4rwy]], [[4rfn]] - hFab anti-HIV + gp120 core<br />
 +
**[[4xnz]], [[4xny]], [[4xmp]] - hFab anti-HIV + gp41<br />
 +
**[[2x7l]], [[5dhz]], [[5dhy]], [[5dhx]], [[5dhv]] – hFab anti-HIV + HIV REV<br />
 +
**[[4r8w]] - hFab anti-HIV + hemagglutinin<br />
 +
**[[4utb]], [[4uta]], [[4ut9]], [[4ut6]] – hFab anti-HIV + dengue envelope protein<br />
 +
**[[1afv]] – mFab anti-HIV + capsid protein C<br />
 +
**[[4qnp]] – mFab anti-HIV + neuraminidase<br />
 +
 +
*Lama Fab: protein complex
 +
**[[3k7u]], [[3k80]] – LgFab + MP18 RNA editing protein <br />
**[[3k7u]], [[3k80]] – LgFab + MP18 RNA editing protein <br />
-
**[[3mj9]] – AhFab HL4E10 + JAML <br />
 
-
**[[3r08]] - AhFab 2C11 + CD3ε<br />
 
-
**[[4hti]] – rFab + TNF ligand<br />
 
-
**[[1g6v]] – bFab + carbonic anhydrase<br />
 
-
**[[4hgk]] – Fab + albumin – shark<br />
 
**[[4ej1]], [[4eiz]], [[4eig]] – LgFab + DHFR <br />
**[[4ej1]], [[4eiz]], [[4eig]] – LgFab + DHFR <br />
**[[3k81]], [[3stb]], [[4dk3]], [[4dk6]], [[4dka]] – LgFab + RNA editing complex protein<br />
**[[3k81]], [[3stb]], [[4dk3]], [[4dk6]], [[4dka]] – LgFab + RNA editing complex protein<br />
Line 259: Line 269:
**[[4n1h]], [[4m3k]] – LgFab + beta-lactamase<br />
**[[4n1h]], [[4m3k]] – LgFab + beta-lactamase<br />
**[[5m95]], [[5m94]], [[4wgw]], [[4wgv]] – LgFab + metal cation transporter<br />
**[[5m95]], [[5m94]], [[4wgw]], [[4wgv]] – LgFab + metal cation transporter<br />
 +
 +
*Other Fab: protein complex
 +
 +
**[[3ld8]], [[3ldb]] – AhFab + bifunctional arginine demethylase <br />
 +
**[[3mj9]] – AhFab HL4E10 + JAML <br />
 +
**[[3r08]] - AhFab 2C11 + CD3ε<br />
 +
**[[1jps]] - hmFab D3H44 + tissue factor<br />
 +
**[[5f3h]], [[5f3b]] - hmFab + growth factor 8<br />
 +
**[[1pkq]] – hmFab 8-18C5 + myelin glycoprotein<br />
 +
**[[2b2x]] – rFab AQC2 + integrin<br />
 +
**[[2r56]] – bFab igE + β-lactoglobulin <br />
 +
**[[1bzq]], [[2p42]], [[2p43]], [[2p44]], [[2p45]], [[2p46]], [[2p47]], [[2p48]], [[2p49]], [[2p4a]] – bFab Cab-Rn05 + RNase<br />
 +
**[[4hti]] – rFab + TNF ligand<br />
 +
**[[1g6v]] – bFab + carbonic anhydrase<br />
 +
**[[4hgk]] – Fab + albumin – shark<br />
**[[5hgg]] – Fab + urokinase-type plasminogen activator - Vicugna<br />
**[[5hgg]] – Fab + urokinase-type plasminogen activator - Vicugna<br />
**[[1jto]], [[1jtp]], [[1jtt]], [[1ri8]], [[1xfp]], [[1zmy]], [[1zv5]], [[1zvh]] – cFab + lysozyme<br />
**[[1jto]], [[1jtp]], [[1jtt]], [[1ri8]], [[1xfp]], [[1zmy]], [[1zv5]], [[1zvh]] – cFab + lysozyme<br />
Line 266: Line 291:
**[[4n9g]] - rmFab + scaffold<br />
**[[4n9g]] - rmFab + scaffold<br />
-
*Fab: protein higher complexes
+
*Human Fab: protein higher complexes
-
**[[3ixx]], [[3ixy]] - mFab E53 + envelope glycoprotein + West Nile virus peptide<br />
 
-
**[[1g9m]], [[1g9n]], [[1gc1]], [[2i5y]], [[2i60]], [[2nxy]], [[2nxz]], [[2ny0]], [[2ny1]], [[2ny2]], [[2ny3]], [[2ny4]], [[2ny5]], [[2ny6]], [[3jwd]], [[3jwo]], [[5a8h]], [[5a7x]], [[4r4h]] - hFab anti-HIV + envelope glycoprotein gp120 + CD4<br />
 
-
**[[5jsa]], [[5js9]], [[5c7k]] - hFab anti-HIV + envelope glycoprotein gp120 + gp41<br />
 
-
**[[4r4n]], [[4r4f]] - hFab anti-HIV + envelope glycoprotein gp120 + M48U1 peptide<br />
 
**[[2wuc]] - hFab 40 + hepatocyte growth factor activator + inhibitor<br />
**[[2wuc]] - hFab 40 + hepatocyte growth factor activator + inhibitor<br />
-
**[[3lqa]], [[2qad]] - hFab anti-HIV + CD4 + gp41<br />
 
**[[3d85]] - hFab 7G10 + IL-12 + IL-23<br />
**[[3d85]] - hFab 7G10 + IL-12 + IL-23<br />
**[[4xwo]] - hFab + ATPase GET3 + Sec22<br />
**[[4xwo]] - hFab + ATPase GET3 + Sec22<br />
Line 283: Line 303:
**[[3bt2]] – hFab anti-UPAR + urokinase-type plasminogen activator + vitronectin<br />
**[[3bt2]] – hFab anti-UPAR + urokinase-type plasminogen activator + vitronectin<br />
**[[3gjf]], [[3hae]] – hFab + β-2-microglobulin + MHC antigen + NYESO peptide<br />
**[[3gjf]], [[3hae]] – hFab + β-2-microglobulin + MHC antigen + NYESO peptide<br />
 +
 +
*Human anti_HIV Fab: protein higher complexes
 +
 +
**[[1g9m]], [[1g9n]], [[1gc1]], [[2i5y]], [[2i60]], [[2nxy]], [[2nxz]], [[2ny0]], [[2ny1]], [[2ny2]], [[2ny3]], [[2ny4]], [[2ny5]], [[2ny6]], [[3jwd]], [[3jwo]], [[5a8h]], [[5a7x]], [[4r4h]] - hFab anti-HIV + envelope glycoprotein gp120 + CD4<br />
 +
**[[5jsa]], [[5js9]], [[5c7k]] - hFab anti-HIV + envelope glycoprotein gp120 + gp41<br />
 +
**[[4r4n]], [[4r4f]] - hFab anti-HIV + envelope glycoprotein gp120 + M48U1 peptide<br />
 +
**[[3lqa]], [[2qad]] - hFab anti-HIV + CD4 + gp41<br />
 +
 +
*Mouse Fab: protein higher complexes
 +
 +
**[[3ixx]], [[3ixy]] - mFab E53 + envelope glycoprotein + West Nile virus peptide<br />
**[[3gb7]], [[2p7t]], [[2h8p]], [[2hfe]], [[2atk]], [[4wfh]], [[4wfg]], [[4wff]], [[4wfe]] - mFab + KcsA K+ channel + ion<br />
**[[3gb7]], [[2p7t]], [[2h8p]], [[2hfe]], [[2atk]], [[4wfh]], [[4wfg]], [[4wff]], [[4wfe]] - mFab + KcsA K+ channel + ion<br />
**[[3or6]], [[3or7]], [[3ogc]], [[3fb7]], [[3f7v]], [[3f7y]], [[3fb5]], [[3fb6]], [[3fb8]], [[3iga]], [[2itc]], [[2itd]], [[2nlj]], [[2bob]], [[2boc]], [[1s5h]], [[1r3i]], [[1r3j]], [[1r3k]], [[1r3l]], [[1k4c]], [[1k4d]], [[3hpl]] - mFab + KcsA K+ channel (mutant) + ion<br />
**[[3or6]], [[3or7]], [[3ogc]], [[3fb7]], [[3f7v]], [[3f7y]], [[3fb5]], [[3fb6]], [[3fb8]], [[3iga]], [[2itc]], [[2itd]], [[2nlj]], [[2bob]], [[2boc]], [[1s5h]], [[1r3i]], [[1r3j]], [[1r3k]], [[1r3l]], [[1k4c]], [[1k4d]], [[3hpl]] - mFab + KcsA K+ channel (mutant) + ion<br />
Line 289: Line 320:
**[[1qkz]] – mFab + protein G prime + major outer membrane protein peptide<br />
**[[1qkz]] – mFab + protein G prime + major outer membrane protein peptide<br />
**[[2ibz]] – mFab + cytochrome bc1 complex + stigmatellin <br />
**[[2ibz]] – mFab + cytochrome bc1 complex + stigmatellin <br />
 +
 +
*Lama Fab: protein higher complexes
 +
**[[3v0a]] – LgFab + BONT/A1 + NTNH<br />
**[[3v0a]] – LgFab + BONT/A1 + NTNH<br />
**[[3sn6]] – LgFab + adrenergic receptor + guanine nucleotide-binding protein<br />
**[[3sn6]] – LgFab + adrenergic receptor + guanine nucleotide-binding protein<br />

Revision as of 08:50, 8 March 2017

3D Structures of Immunoglobulin

Updated on 08-March-2017

Humanized mouse antibody (hmFab) is a modified mFab which resembles more hFab.
Broadly neutralizing Fab and Neutralizing Fab are anti-HIV Fab.
Lama antibodies or nanobodies are natural single-domain antibodies containing just the heavy chain.

Proteopedia Page Contributors and Editors (what is this?)

Joel L. Sussman, Michal Harel, Jaime Prilusky

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