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==4jhp== | ==4jhp== | ||
<StructureSection load='4jhp' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='4jhp' size='340' side='right' caption='Caption for this structure' scene=''> | ||
| - | + | 4jhp is a lipid binding protein. It is composed of two macromolecules described as retinal rod rhodopsin sensitive cGMP 3',5’cyclic phosphodiesterase subunit delta as well as X-linked retinitis pigmentosa GTPase regulator. The retinitis pegmentosa GTPase regulator, RPGR, may be mutated causing severe eye disease. It is also located in a region considered a ciliary zone. The European Molecular Biology Organization reports proposes that RPGR is being recruited to place lapidated cargo into the cilia. Oxford academic also has an article about ciliary trafficking defects. Examples given for ciliopathies it may cause are Joubert Syndrome, Bardet-Biedel Syndrome, and forms of retinitis pigmentosa. | |
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== Structure == | == Structure == | ||
Revision as of 20:51, 8 March 2017
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