5j50
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of tetrameric jacalin complexed with Gal beta-(1,3) GalNAc-alpha-OPNP== | |
| + | <StructureSection load='5j50' size='340' side='right' caption='[[5j50]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5j50]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J50 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J50 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NPO:P-NITROPHENOL'>NPO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ugw|1ugw]], [[1jac|1jac]], [[1kuj|1kuj]], [[1ws5|1ws5]], [[1ws4|1ws4]], [[1uh0|1uh0]], [[1m26|1m26]], [[1ugx|1ugx]], [[1uh1|1uh1]], [[1ugy|1ugy]], [[1ku8|1ku8]], [[4r6n|4r6n]], [[4r6o|4r6o]], [[4r6p|4r6p]], [[4r6q|4r6q]], [[4r6r|4r6r]], [[5j4x|5j4x]], [[5j51|5j51]], [[5j52|5j52]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j50 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j50 OCA], [http://pdbe.org/5j50 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j50 RCSB], [http://www.ebi.ac.uk/pdbsum/5j50 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j50 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LECA_ARTIN LECA_ARTIN]] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum. [[http://www.uniprot.org/uniprot/LECB3_ARTIN LECB3_ARTIN]] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum. | ||
| - | + | ==See Also== | |
| - | + | *[[Agglutinin|Agglutinin]] | |
| - | + | __TOC__ | |
| - | [[ | + | </StructureSection> |
| - | [[Category: | + | [[Category: Artocarpus integer]] |
| - | [[Category: Abhinav, K | + | [[Category: Abhinav, K V]] |
[[Category: Sharma, K]] | [[Category: Sharma, K]] | ||
[[Category: Surolia, A]] | [[Category: Surolia, A]] | ||
| + | [[Category: Vijayan, M]] | ||
| + | [[Category: Beta-prism i fold]] | ||
| + | [[Category: Galactose specific lectin]] | ||
| + | [[Category: Plant lectin]] | ||
| + | [[Category: Post translational proteolysis]] | ||
| + | [[Category: Reducing and non-reducing sugar]] | ||
| + | [[Category: Sugar binding protein]] | ||
| + | [[Category: T-antigen binding protein]] | ||
Revision as of 09:25, 10 March 2017
Structure of tetrameric jacalin complexed with Gal beta-(1,3) GalNAc-alpha-OPNP
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