5amf
From Proteopedia
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==Crystal structure of the bromodomain of human surface epitope engineered BRD1A in complex with 3D Consortium fragment Ethyl 4,5,6,7- tetrahydro-1H-indazole-5-carboxylate (SGC - Diamond I04-1 fragment screening)== | ==Crystal structure of the bromodomain of human surface epitope engineered BRD1A in complex with 3D Consortium fragment Ethyl 4,5,6,7- tetrahydro-1H-indazole-5-carboxylate (SGC - Diamond I04-1 fragment screening)== | ||
<StructureSection load='5amf' size='340' side='right' caption='[[5amf]], [[Resolution|resolution]] 1.75Å' scene=''> | <StructureSection load='5amf' size='340' side='right' caption='[[5amf]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TWL:ETHYL+(5R)-4,5,6,7-TETRAHYDRO-1H-INDAZOLE-5-CARBOXYLATE'>TWL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TWL:ETHYL+(5R)-4,5,6,7-TETRAHYDRO-1H-INDAZOLE-5-CARBOXYLATE'>TWL</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ame|5ame]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ame|5ame]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5amf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5amf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5amf RCSB], [http://www.ebi.ac.uk/pdbsum/5amf PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5amf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5amf OCA], [http://pdbe.org/5amf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5amf RCSB], [http://www.ebi.ac.uk/pdbsum/5amf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5amf ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/BRD1_HUMAN BRD1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.<ref>PMID:16387653</ref> <ref>PMID:21880731</ref> | [[http://www.uniprot.org/uniprot/BRD1_HUMAN BRD1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.<ref>PMID:16387653</ref> <ref>PMID:21880731</ref> | ||
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| + | ==See Also== | ||
| + | *[[Bromodomain-containing protein|Bromodomain-containing protein]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 09:52, 10 March 2017
Crystal structure of the bromodomain of human surface epitope engineered BRD1A in complex with 3D Consortium fragment Ethyl 4,5,6,7- tetrahydro-1H-indazole-5-carboxylate (SGC - Diamond I04-1 fragment screening)
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Categories: Arrowsmith, C H | Bountra, C | Bowkett, D | Bradley, A | Brandao-Neto, J | Brennan, P | Burgess-Brown, N | Collins, P | Cox, O | Delft, F von | Douangamath, A | Edwards, E | Fairhead, M | Krojer, T | Ng, J T | Pearce, N M | Strain-Damerell, C | Talon, R | Wright, N | Bromodomain | Diamond i04-1 | Epigenetic | Fragmentscreening | Histone-binding protein | Sgc | Structural genomic
