5lfw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "5lfw" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5lfw is ON HOLD
+
==Lambda-[Ru(phen)2(dppz)]2+ bound to a short substituted DNA sequence==
 +
<StructureSection load='5lfw' size='340' side='right' caption='[[5lfw]], [[Resolution|resolution]] 1.28&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[5lfw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LFW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LFW FirstGlance]. <br>
 +
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene>, <scene name='pdbligand=RKP:LAMBDA-RU(PHEN)2(DPPZ)+COMPLEX'>RKP</scene></td></tr>
 +
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5BT:5-BROMO-2-DEOXYCYTIDINE'>5BT</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lfw OCA], [http://pdbe.org/5lfw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lfw RCSB], [http://www.ebi.ac.uk/pdbsum/5lfw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lfw ProSAT]</span></td></tr>
 +
</table>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
X-ray crystal structures of three Lambda-[Ru(L)2 dppz]2+ complexes (dppz=dipyridophenazine; L=1,10-phenanthroline (phen), 2,2'-bipyridine (bpy)) bound to d((5BrC)GGC/GCCG) showed the compounds intercalated at a 5'-CG-3' step. The compounds bind through canted intercalation, with the binding angle determined by the guanine NH2 group, in contrast to symmetrical intercalation previously observed at 5'-TA-3' sites. This result suggests that canted intercalation is preferred at 5'-CG-3' sites even though the site itself is symmetrical, and we hypothesise that symmetrical intercalation in a 5'-CG-3' step could give rise to a longer luminescence lifetime than canted intercalation.
-
Authors: Hall, J.P., Cardin, C.J.
+
Guanine Can Direct Binding Specificity of Ru-dipyridophenazine (dppz) Complexes to DNA through Steric Effects.,Hall JP, Gurung SP, Henle J, Poidl P, Andersson J, Lincoln P, Winter G, Sorensen T, Cardin DJ, Brazier JA, Cardin CJ Chemistry. 2017 Jan 19. doi: 10.1002/chem.201605508. PMID:28105682<ref>PMID:28105682</ref>
-
Description: Lambda-[Ru(phen)2(dppz)]2+ bound to a short substituted DNA sequence
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
[[Category: Unreleased Structures]]
+
</div>
-
[[Category: Hall, J.P]]
+
<div class="pdbe-citations 5lfw" style="background-color:#fffaf0;"></div>
-
[[Category: Cardin, C.J]]
+
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Cardin, C J]]
 +
[[Category: Hall, J P]]
 +
[[Category: Dna]]
 +
[[Category: Intercalation]]
 +
[[Category: Light-switch]]
 +
[[Category: Ruthenium]]

Revision as of 17:41, 10 March 2017

Lambda-[Ru(phen)2(dppz)]2+ bound to a short substituted DNA sequence

5lfw, resolution 1.28Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5lfw"
Personal tools