5fve
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Helicobacter pylori beta clamp in complex with 3, 4-Difluorobenzamide== | |
| - | + | <StructureSection load='5fve' size='340' side='right' caption='[[5fve]], [[Resolution|resolution]] 2.07Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5fve]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FVE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FVE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2HO:3,4-DIFLUOROBENZAMIDE'>2HO</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fve OCA], [http://pdbe.org/5fve PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fve RCSB], [http://www.ebi.ac.uk/pdbsum/5fve PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fve ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DPO3B_HELPY DPO3B_HELPY]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: DNA-directed DNA polymerase]] | ||
| + | [[Category: Gourinath, S]] | ||
[[Category: Pandey, P]] | [[Category: Pandey, P]] | ||
| - | [[Category: | + | [[Category: Dna clamp]] |
| + | [[Category: Sliding clamp]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 01:30, 11 March 2017
Crystal Structure of Helicobacter pylori beta clamp in complex with 3, 4-Difluorobenzamide
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