5if8

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-	'''Unreleased structure'''
-	The entry 5if8 is ON HOLD until Paper Publication	+	==Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-2643 5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine==
-		+	<StructureSection load='5if8' size='340' side='right' caption='[[5if8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-	Authors:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5if8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IF8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IF8 FirstGlance]. <br>
-	Description:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6AX:5-[(4-CHLOROPHENYL)METHYL]-1,3,4-OXADIAZOL-2-AMINE'>6AX</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	[[Category: Unreleased Structures]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iuj|4iuj]], [[5ieq|5ieq]], [[5if2|5if2]], [[5if5|5if5]], [[5if7|5if7]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5if8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5if8 OCA], [http://pdbe.org/5if8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5if8 RCSB], [http://www.ebi.ac.uk/pdbsum/5if8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5if8 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PA_I33A0 PA_I33A0]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Structural genomic]]
		+	[[Category: Flu]]
		+	[[Category: Fragment screening]]
		+	[[Category: Niaid]]
		+	[[Category: Ssgcid]]
		+	[[Category: Std nmr]]
		+	[[Category: Viral protein]]

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Revision as of 01:34, 11 March 2017

Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-2643 5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine

spinqualitylabelsall models 5if8, resolution 2.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Structural highlights 5if8 is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: , , , , Related: 4iuj, 5ieq, 5if2, 5if5, 5if7 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [PA_I33A0] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication. Contents 1 Structural highlights 2 Function