5t01

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'''Unreleased structure'''
 
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The entry 5t01 is ON HOLD until Paper Publication
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==Human c-Jun DNA binding domain homodimer in complex with methylated DNA==
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<StructureSection load='5t01' size='340' side='right' caption='[[5t01]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5t01]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T01 FirstGlance]. <br>
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Description:
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5szx|5szx]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t01 OCA], [http://pdbe.org/5t01 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t01 RCSB], [http://www.ebi.ac.uk/pdbsum/5t01 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t01 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/JUN_HUMAN JUN_HUMAN]] Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.<ref>PMID:10995748</ref> <ref>PMID:17210646</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Cheng, X]]
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[[Category: Hong, S]]
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[[Category: Horton, J R]]
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[[Category: 5-methylcytosine]]
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[[Category: Ap-1]]
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[[Category: Basic leucine-zipper]]
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[[Category: Bzip]]
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[[Category: Bzlf-1]]
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[[Category: Dna methylation]]
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[[Category: Ebv]]
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[[Category: Epstein-barr virus]]
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[[Category: Transcription factor]]
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[[Category: Transcription regulator-dna complex]]
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[[Category: Zebra]]
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[[Category: Zta]]

Revision as of 09:40, 11 March 2017

Human c-Jun DNA binding domain homodimer in complex with methylated DNA

5t01, resolution 1.89Å

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