5t01
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Human c-Jun DNA binding domain homodimer in complex with methylated DNA== | |
- | + | <StructureSection load='5t01' size='340' side='right' caption='[[5t01]], [[Resolution|resolution]] 1.89Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5t01]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T01 FirstGlance]. <br> | |
- | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr> | |
- | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5szx|5szx]]</td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t01 OCA], [http://pdbe.org/5t01 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t01 RCSB], [http://www.ebi.ac.uk/pdbsum/5t01 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t01 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/JUN_HUMAN JUN_HUMAN]] Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.<ref>PMID:10995748</ref> <ref>PMID:17210646</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Cheng, X]] | ||
+ | [[Category: Hong, S]] | ||
+ | [[Category: Horton, J R]] | ||
+ | [[Category: 5-methylcytosine]] | ||
+ | [[Category: Ap-1]] | ||
+ | [[Category: Basic leucine-zipper]] | ||
+ | [[Category: Bzip]] | ||
+ | [[Category: Bzlf-1]] | ||
+ | [[Category: Dna methylation]] | ||
+ | [[Category: Ebv]] | ||
+ | [[Category: Epstein-barr virus]] | ||
+ | [[Category: Transcription factor]] | ||
+ | [[Category: Transcription regulator-dna complex]] | ||
+ | [[Category: Zebra]] | ||
+ | [[Category: Zta]] |
Revision as of 09:40, 11 March 2017
Human c-Jun DNA binding domain homodimer in complex with methylated DNA
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