5uen
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the human adenosine A1 receptor A1AR-bRIL in complex with the covalent antagonist DU172 at 3.2A resolution== | |
| - | + | <StructureSection load='5uen' size='340' side='right' caption='[[5uen]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5uen]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UEN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DU1:4-{[3-(8-CYCLOHEXYL-2,6-DIOXO-1-PROPYL-1,2,6,7-TETRAHYDRO-3H-PURIN-3-YL)PROPYL]CARBAMOYL}BENZENE-1-SULFONYL+FLUORIDE'>DU1</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uen OCA], [http://pdbe.org/5uen PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uen RCSB], [http://www.ebi.ac.uk/pdbsum/5uen PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uen ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/AA1R_HUMAN AA1R_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Christopoulos, A]] | ||
| + | [[Category: Glukhova, A]] | ||
| + | [[Category: Jorg, M]] | ||
| + | [[Category: May, L T]] | ||
| + | [[Category: Nguyen, A T]] | ||
| + | [[Category: Scammells, P J]] | ||
| + | [[Category: Sexton, P M]] | ||
| + | [[Category: Thal, D M]] | ||
| + | [[Category: Vecchio, E A]] | ||
| + | [[Category: Adenosine]] | ||
| + | [[Category: Gpcr]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Receptor]] | ||
| + | [[Category: Transmembrane]] | ||
Revision as of 09:43, 11 March 2017
Crystal structure of the human adenosine A1 receptor A1AR-bRIL in complex with the covalent antagonist DU172 at 3.2A resolution
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Categories: Christopoulos, A | Glukhova, A | Jorg, M | May, L T | Nguyen, A T | Scammells, P J | Sexton, P M | Thal, D M | Vecchio, E A | Adenosine | Gpcr | Membrane protein | Receptor | Transmembrane
