5l87
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.== | |
| - | + | <StructureSection load='5l87' size='340' side='right' caption='[[5l87]], [[Resolution|resolution]] 0.87Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5l87]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L87 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L87 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6RD:5-(1~{H}-INDOL-3-YLMETHYL)-1-METHYL-~{N}-(NAPHTHALEN-1-YLMETHYL)-6,7-DIHYDRO-4~{H}-PYRAZOLO[4,3-C]PYRIDINE-3-CARBOXAMIDE'>6RD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2w84|2w84]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l87 OCA], [http://pdbe.org/5l87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l87 RCSB], [http://www.ebi.ac.uk/pdbsum/5l87 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l87 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Dawidowski, M]] | [[Category: Dawidowski, M]] | ||
[[Category: Emmanouilidis, L]] | [[Category: Emmanouilidis, L]] | ||
| + | [[Category: Popowicz, G M]] | ||
[[Category: Sattler, M]] | [[Category: Sattler, M]] | ||
| - | [[Category: | + | [[Category: Glycosome]] |
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Protein-protein interaction inhibitor]] | ||
| + | [[Category: Structure-based drug discovery]] | ||
| + | [[Category: Trypanosomiasis]] | ||
Revision as of 19:16, 11 March 2017
Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.
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