Sandbox Reserved 1061

From Proteopedia

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== Biological Function ==
== Biological Function ==
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Caspase-6 is a protease involved in '''apoptosis'''. It is most notably involved in neurodegenerative diseases, such as Alzheimer's disease and dementia.
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Caspase-6 is a member of the Cysteine-Aspartic protease family, and involved in '''apoptosis'''. It is most notably involved in neurodegenerative diseases, such as Alzheimer's disease and dementia.
== Structural Overview ==
== Structural Overview ==
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== Mechanism of Action ==
== Mechanism of Action ==
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Mechanism is unknown as of right now. The active sight is known to be HIS-121, CYS-163, and GLU-174.
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Mechanism is unknown as of right now. The active sight is known to be HIS-121, CYS-163, and GLU-174. It is tightly regulated by Zinc binding to an allosteric site.
== Zinc Ligand(s) ==
== Zinc Ligand(s) ==
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The Zinc ligand is known to inhibit the
== Other Ligands ==
== Other Ligands ==
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Other ligands that bind to Caspase-6 are caspase-8, which is activated within the caspase-chain by Caspase 6.
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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</StructureSection>
</StructureSection>
== References ==
== References ==
<references/>
<references/>
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

Revision as of 12:27, 14 March 2017

Text To Be Displayed</scene>
Figure Legend
Figure Legend
This Sandbox is Reserved from 02/09/2015, through 05/31/2016 for use in the course "CH462: Biochemistry 2" taught by Geoffrey C. Hoops at the Butler University. This reservation includes Sandbox Reserved 1051 through Sandbox Reserved 1080.
To get started:
  • Click the edit this page tab at the top. Save the page after each step, then edit it again.
  • Click the 3D button (when editing, above the wikitext box) to insert Jmol.
  • show the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
  • Add a description of your scene. Use the buttons above the wikitext box for bold, italics, links, headlines, etc.

More help: Help:Editing

Human Caspase-6

Caspase-6

Drag the structure with the mouse to rotate

References

  1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

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