5pl5

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m (Protected "5pl5" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5pl5 is ON HOLD
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==PanDDA analysis group deposition -- Crystal Structure of JMJD2D after initial refinement with no ligand modelled (structure 126)==
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<StructureSection load='5pl5' size='340' side='right' caption='[[5pl5]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
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Authors: Krojer, T.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5pl5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5PL5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5PL5 FirstGlance]. <br>
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Description: PanDDA analysis group deposition --Crystal Structure of JMJD2D after initial refinement with no ligand modelled (structure 126)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5pl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5pl5 OCA], [http://pdbe.org/5pl5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5pl5 RCSB], [http://www.ebi.ac.uk/pdbsum/5pl5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5pl5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/KDM4D_HUMAN KDM4D_HUMAN]] Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.<ref>PMID:16603238</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C]]
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[[Category: Bradley, A R]]
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[[Category: Brandao-Neto, J]]
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[[Category: Brennan, P E]]
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[[Category: Burgess-Brown, N]]
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[[Category: Collins, P]]
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[[Category: Cox, O]]
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[[Category: Delft, F von]]
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[[Category: Dias, A]]
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[[Category: Douangamath, A]]
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[[Category: Edwards, A]]
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[[Category: Fairhead, M]]
[[Category: Krojer, T]]
[[Category: Krojer, T]]
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[[Category: MacLean, E]]
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[[Category: Ng, J]]
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[[Category: Oppermann, U]]
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[[Category: Pearce, N M]]
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[[Category: Renjie, Z]]
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[[Category: Sethi, R]]
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[[Category: Szykowska, A]]
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[[Category: Talon, R]]
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[[Category: Vollmar, M]]
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[[Category: Wright, N]]
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[[Category: Epigenetic]]
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[[Category: Jmj domain]]
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[[Category: Oxidoreductase]]
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[[Category: Pandda]]
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[[Category: Sgc - diamond i04-1 fragment screening]]

Revision as of 21:35, 15 March 2017

PanDDA analysis group deposition -- Crystal Structure of JMJD2D after initial refinement with no ligand modelled (structure 126)

5pl5, resolution 1.57Å

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