Catechol O-methyltransferase
From Proteopedia
(Difference between revisions)
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**[[4pyq]] – rCOMT (mutant) + ureido-benzamidine<BR /> | **[[4pyq]] – rCOMT (mutant) + ureido-benzamidine<BR /> | ||
**[[1vid]] – rCOMT + SAM + dinitrocatechol <BR /> | **[[1vid]] – rCOMT + SAM + dinitrocatechol <BR /> | ||
| - | **[[1jr4]], [[3hvh]], [[3hvi]], [[3hvj]], [[3hvk]], [[3a7d]], [[3nw9]], [[3nwb]], [[3nwe]] – rCOMT + inhibitor<BR /> | + | **[[1jr4]], [[3hvh]], [[3hvi]], [[3hvj]], [[3hvk]], [[3a7d]], [[3nw9]], [[3nwb]], [[3nwe]], [[5k01]], [[5k03]], [[5k05]], [[5k09]], [[5k0b]], [[5k0c]], [[5k0e]], [[5k0f]], [[5k0g]], [[5k0j]], [[5k0l]], [[5k0n]], [[5lqa]], [[5lqc]], [[5lqj]], [[5lqk]], [[5lqn]], [[5lqr]], [[5lqu]], [[5lr6]] – rCOMT + inhibitor<BR /> |
**[[4p7k]], [[4pyl]] – rCOMT + sinefungin<BR /> | **[[4p7k]], [[4pyl]] – rCOMT + sinefungin<BR /> | ||
| - | **[[3oe4]], [[3oe5]], [[3ozr]], [[3ozs]], [[3ozt]], [[3r6t]] – rCOMT (mutant) + inhibitor<BR /> | + | **[[3oe4]], [[3oe5]], [[3ozr]], [[3ozs]], [[3ozt]], [[3r6t]], [[5p8w]] – rCOMT (mutant) + inhibitor<BR /> |
**[[1h1d]], [[2cl5]], [[2zvj]], [[3s68]] – rCOMT + inhibitor + SAM<BR /> | **[[1h1d]], [[2cl5]], [[2zvj]], [[3s68]] – rCOMT + inhibitor + SAM<BR /> | ||
| + | **[[5fhq]] – rCOMT + SAM + dinitrocatechol <BR /> | ||
| + | **[[5fhr]] – rCOMT (mutant) + SAM + dinitrocatechol <BR /> | ||
**[[2avd]] – hCOMT + SAM – human <BR /> | **[[2avd]] – hCOMT + SAM – human <BR /> | ||
| - | **[[3bwm]], [[3a7e]] – hCOMT + SAM + dinitrocatechol <BR /> | + | **[[3bwm]], [[3a7e]], [[5lsa]] – hCOMT + SAM + dinitrocatechol <BR /> |
**[[3bwy]], [[4xuc]] – hCOMT (mutant) + SAM + dinitrocatechol <BR /> | **[[3bwy]], [[4xuc]] – hCOMT (mutant) + SAM + dinitrocatechol <BR /> | ||
| + | **[[4xue]] – hCOMT + SAM + catechol mimic<BR /> | ||
| + | **[[4xuc]], [[4xud]] – hCOMT (mutant) + SAM + catechol mimic<BR /> | ||
**[[4p58]] – mCOMT + inhibitor <BR /> | **[[4p58]] – mCOMT + inhibitor <BR /> | ||
}} | }} | ||
Revision as of 10:35, 28 March 2017
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3D Structures of catechol O-methyltransferase
Updated on 28-March-2017
References
- ↑ Tsuji E, Okazaki K, Isaji M, Takeda K. Crystal structures of the Apo and Holo form of rat catechol-O-methyltransferase. J Struct Biol. 2008 Dec 10. PMID:19111934 doi:S1047-8477(08)00293-1
- ↑ Muller T. Catechol-O-methyltransferase inhibitors in Parkinson's disease. Drugs. 2015 Feb;75(2):157-74. doi: 10.1007/s40265-014-0343-0. PMID:25559423 doi:http://dx.doi.org/10.1007/s40265-014-0343-0
