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5iuq
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Galectin-3c in complex with Bisamido-thiogalactoside derivative 4== | |
| - | + | <StructureSection load='5iuq' size='340' side='right' caption='[[5iuq]], [[Resolution|resolution]] 1.12Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5iuq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IUQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IUQ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6E1:3-DEOXY-3-[(2,3,5,6-TETRAFLUORO-4-METHOXYBENZENE-1-CARBONYL)AMINO]-BETA-D-GALACTOPYRANOSYL+3-DEOXY-3-[(2,3,5,6-TETRAFLUORO-4-METHOXYBENZENE-1-CARBONYL)AMINO]-1-THIO-BETA-D-GALACTOPYRANOSIDE'>6E1</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4blj|4blj]], [[4bli|4bli]], [[4bm8|4bm8]]</td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iuq OCA], [http://pdbe.org/5iuq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iuq RCSB], [http://www.ebi.ac.uk/pdbsum/5iuq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iuq ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LEG3_HUMAN LEG3_HUMAN]] Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.<ref>PMID:15181153</ref> <ref>PMID:19594635</ref> <ref>PMID:19616076</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Aurelius, O]] | ||
[[Category: Engstrom, O]] | [[Category: Engstrom, O]] | ||
| + | [[Category: Hakansson, M]] | ||
[[Category: Leffler, H]] | [[Category: Leffler, H]] | ||
| - | [[Category: | + | [[Category: Logan, D T]] |
| - | [[Category: Noresson, A | + | [[Category: Nilsson, U J]] |
| - | [[Category: Oberg, C | + | [[Category: Noresson, A L]] |
| - | [[Category: | + | [[Category: Oberg, C T]] |
| - | [[Category: | + | [[Category: Sundin, A P]] |
| - | [[Category: | + | [[Category: Crd]] |
| + | [[Category: Gal3c]] | ||
| + | [[Category: Sugar binding protein]] | ||
Revision as of 13:44, 29 March 2017
Galectin-3c in complex with Bisamido-thiogalactoside derivative 4
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Categories: Aurelius, O | Engstrom, O | Hakansson, M | Leffler, H | Logan, D T | Nilsson, U J | Noresson, A L | Oberg, C T | Sundin, A P | Crd | Gal3c | Sugar binding protein
