User:Luke Edward Severinac/Sandbox 1

spinqualitylabelsall models This is the 3D PDB protein that was presented in class, 4FXO. (Caspase-6) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

You may include any references to papers as in: the use of JSmol in Proteopedia ^[1] or to the article describing Jmol ^[2] to the rescue.

Contents 1 4FXO 1.1 Image of protein 2 Active Site 3 properties 4 Catalytic triad 5 Relevance 6 Structural highlights

4FXO

Image of protein

Active Site

Caspase 6 is a part of the cystine aspartase family that cleaves proteins at the TEVD sequence. in its monomeric form with protein ligand bound, its catalytic residues are , , and . Together, these residues form a that cleaves .

properties

If is , the activity of this protein is inhibited.

If binds to the protein, the activity of the active site is inhibited.

Inactive state of caspase 6:

Catalytic triad

Relevance

Structural highlights

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.