Complement C3

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Line 28: Line 28:
**[[2a73]] – hCC3 – human <br />
**[[2a73]] – hCC3 – human <br />
**[[1ghq]] – hCC3 residues 996-1300 + Epstein-Barr virus receptor <br />
**[[1ghq]] – hCC3 residues 996-1300 + Epstein-Barr virus receptor <br />
 +
**[[4zh1]] – hCC3 + complement factor H <br />
**[[2b39]] – bCC3 – bovine <br />
**[[2b39]] – bCC3 – bovine <br />
Line 36: Line 37:
*Complement C3b
*Complement C3b
-
**[[2i07]] – hCC3 β+α’ chains<br />
+
**[[2i07]], [[5fo7]] – hCC3 β+α’ chains<br />
-
**[[2icf]] – hCC3 α+β chains + protein CRIG<br />
+
**[[5fob]] – hCC3 β+α’ chains + inhibitor<br />
 +
**[[5fo9]] – hCC3 β+α’ chains + protein<br />
 +
**[[5foa]], [[5f08]], [[2icf]], [[2wii]] – hCC3 α+β chains + protein <br />
**[[3g6j]] – hCC3 α+β chains + antibody<br />
**[[3g6j]] – hCC3 α+β chains + antibody<br />
**[[2xwb]] – hCC3 α+β chains + complement factor B + complement factor D<br />
**[[2xwb]] – hCC3 α+β chains + complement factor B + complement factor D<br />
**[[2xwj]] – hCC3 α+β chains (mutant) + complement factor B<br />
**[[2xwj]] – hCC3 α+β chains (mutant) + complement factor B<br />
-
**[[2wii]] – hCC3 α+β chains + complement factor H 1-4 sushi domains<br />
+
**[[3l5n]], [[3ohx]] – hCC3 α+β chains + protein inhibitor<br />
-
**[[3l5n]], [[3ohx]] – hCC3 α+β chains + staphylococcal complement inhibitor<br />
+
**[[2win]] – hCC3 α+β chains + complement factor B BB fragment + protein inhibitor<br />
-
**[[2win]] – hCC3 α+β chains + complement factor B BB fragment + staphylococcal complement inhibitor<br />
+
*Complement C3c
*Complement C3c
Line 55: Line 57:
*Complement C3d
*Complement C3d
 +
**[[5fcr]] – CC3 - mouse <br />
**[[1c3d]] – hCC3 (mutant) <br />
**[[1c3d]] – hCC3 (mutant) <br />
**[[1w2s]], [[3oed]] – hCC3 1-2 sushi domains + complement receptor type 2 precursor<br />
**[[1w2s]], [[3oed]] – hCC3 1-2 sushi domains + complement receptor type 2 precursor<br />
Line 64: Line 67:
**[[2xqw]] – hCC3 + complement factor H 19-20 sushi domains<br />
**[[2xqw]] – hCC3 + complement factor H 19-20 sushi domains<br />
**[[3rj3]] – hCC3 α chain fragment + complement factor H-related protein<br />
**[[3rj3]] – hCC3 α chain fragment + complement factor H-related protein<br />
 +
**[[5mt0]], [[5mt4]], [[5tca]], [[5tcc]], [[5fbe]], [[5fbi]], [[5fck]]
 +
– hCC3 + inhibitor<br />
**[[1qqf]] – rCC3 G fragment - rat <br />
**[[1qqf]] – rCC3 G fragment - rat <br />
**[[1qsj]] – rCC3 G fragment (mutant) <br />
**[[1qsj]] – rCC3 G fragment (mutant) <br />

Revision as of 08:08, 4 April 2017

Structure of human glycosylated complement C3b α (magenta) and β (salmon) chains complex with protein CRIG (cyan) and Ca+2 ion (green) (PDB code 2icf).

Drag the structure with the mouse to rotate

3D structures of complement C3

Updated on 04-April-2017

– hCC3 + inhibitor



References

  1. Sahu A, Lambris JD. Structure and biology of complement protein C3, a connecting link between innate and acquired immunity. Immunol Rev. 2001 Apr;180:35-48. PMID:11414361
  2. Wiesmann C, Katschke KJ, Yin J, Helmy KY, Steffek M, Fairbrother WJ, McCallum SA, Embuscado L, DeForge L, Hass PE, van Lookeren Campagne M. Structure of C3b in complex with CRIg gives insights into regulation of complement activation. Nature. 2006 Nov 9;444(7116):217-20. Epub 2006 Oct 15. PMID:17051150 doi:10.1038/nature05263

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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