CREB-binding protein

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**[[1wo3]], [[1wo4]], [[1wo5]], [[1wo6]], [[1wo7]] – hCBP zinc finger domain (mutant) – human - NMR <br />
**[[1wo3]], [[1wo4]], [[1wo5]], [[1wo6]], [[1wo7]] – hCBP zinc finger domain (mutant) – human - NMR <br />
**[[2d82]] – hCBP bromodomain - NMR<br />
**[[2d82]] – hCBP bromodomain - NMR<br />
-
**[[3dwy]] – hCBP bromodomain <br />
+
**[[3dwy]], [[4ouf]], [[4whu]] – hCBP bromodomain <br />
-
**[[3p1c]], [[3p1d]], [[3p1e]], [[3p1f]], [[3svh]], [[4a9k]] – hCBP bromodomain + small molecule<br />
+
**[[3p1c]], [[3p1d]], [[3p1e]], [[3p1f]], [[3svh]], [[4a9k]], [[4tqn]], [[4ts8]], [[4yk0]], [[5cgp]], [[5dbm]], [[5eic]], [[5eng]], [[5ep7]], [[5h85]], [[5i83]], [[5i86]], [[5i89]], [[5i8b]], [[5i8g]], [[5j0d]], [[5ktu]], [[5ktw]], [[5ktx]], [[5tb6]] – hCBP bromodomain + inhibitor<br />
-
**[[2l84]], [[2l85]] – hCBP bromodomain + small molecule - NMR<br />
+
**[[2l84]], [[2l85]] – hCBP bromodomain + inhibitor - NMR<br />
*CBP complex with protein
*CBP complex with protein
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**[[2ka6]] – mCBP TAZ2 domain + STAT1-TAD - NMR<br />
**[[2ka6]] – mCBP TAZ2 domain + STAT1-TAD - NMR<br />
**[[2ka4]] – mCBP TAZ2 domain + STAT2-TAD - NMR<br />
**[[2ka4]] – mCBP TAZ2 domain + STAT2-TAD - NMR<br />
 +
**[[2n1a]] – hCBP + small ubiquitin-related modifier - NMR<br />
 +
**[[5jem]] – hCBP residues 2065-2111 + interferon-3<br />
**[[1kdx]] – mCBP KIX domain + CREB kinase inducible domain - NMR<br />
**[[1kdx]] – mCBP KIX domain + CREB kinase inducible domain - NMR<br />
**[[2kje]] – hCBP TAZ2 domain + adenoviral E1A peptide - NMR<br />
**[[2kje]] – hCBP TAZ2 domain + adenoviral E1A peptide - NMR<br />

Revision as of 07:26, 5 April 2017

Human CREB-binding protein with acetyllysine complex with SCN- and K+ (purple) ions 3p1c

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3D Structures of CREB-binding protein

Updated on 05-April-2017

References

  1. Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, Goodman RH. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature. 1993 Oct 28;365(6449):855-9. PMID:8413673 doi:http://dx.doi.org/10.1038/365855a0
  2. Petrij F, Giles RH, Dauwerse HG, Saris JJ, Hennekam RC, Masuno M, Tommerup N, van Ommen GJ, Goodman RH, Peters DJ, et al.. Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP. Nature. 1995 Jul 27;376(6538):348-51. PMID:7630403 doi:http://dx.doi.org/10.1038/376348a0
  3. Filippakopoulos P, Picaud S, Mangos M, Keates T, Lambert JP, Barsyte-Lovejoy D, Felletar I, Volkmer R, Muller S, Pawson T, Gingras AC, Arrowsmith CH, Knapp S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell. 2012 Mar 30;149(1):214-31. PMID:22464331 doi:10.1016/j.cell.2012.02.013

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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