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5kgn

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'''Unreleased structure'''
 
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The entry 5kgn is ON HOLD until Paper Publication
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==1.95A resolution structure of independent phosphoglycerate mutase from C. elegans in complex with a macrocyclic peptide inhibitor (2d)==
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<StructureSection load='5kgn' size='340' side='right' caption='[[5kgn]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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Authors: Lovell, S., Mehzabeen, N., Battaile, K.P., Yu, H., Dranchak, P., MacArthur, R., Li, Z., Carlow, T., Suga, H., Inglese, J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5kgn]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KGN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KGN FirstGlance]. <br>
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Description: 1.95A resolution structure of independent phosphoglycerate mutase from C. elegans in complex with a macrocyclic peptide inhibitor (2d)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kgm|5kgm]], [[5kgl|5kgl]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoglycerate_mutase_(2,3-diphosphoglycerate-independent) Phosphoglycerate mutase (2,3-diphosphoglycerate-independent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.2.12 5.4.2.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kgn OCA], [http://pdbe.org/5kgn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kgn RCSB], [http://www.ebi.ac.uk/pdbsum/5kgn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kgn ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GPMI_CAEEL GPMI_CAEEL]] Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.<ref>PMID:15234973</ref> <ref>PMID:17897734</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Battaile, K P]]
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[[Category: Carlow, T]]
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[[Category: Dranchak, P]]
[[Category: Inglese, J]]
[[Category: Inglese, J]]
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[[Category: Li, Z]]
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[[Category: Lovell, S]]
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[[Category: MacArthur, R]]
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[[Category: Mehzabeen, N]]
[[Category: Suga, H]]
[[Category: Suga, H]]
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[[Category: Battaile, K.P]]
 
[[Category: Yu, H]]
[[Category: Yu, H]]
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[[Category: Dranchak, P]]
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[[Category: Coupled enzyme assay]]
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[[Category: Lovell, S]]
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[[Category: High throughput enzymology]]
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[[Category: Mehzabeen, N]]
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[[Category: Ht]]
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[[Category: Li, Z]]
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[[Category: Isomerase]]
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[[Category: Macarthur, R]]
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[[Category: Metal binding]]
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[[Category: Carlow, T]]
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[[Category: Rapid system]]
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[[Category: Structure activity relationship]]

Revision as of 13:27, 5 April 2017

1.95A resolution structure of independent phosphoglycerate mutase from C. elegans in complex with a macrocyclic peptide inhibitor (2d)

5kgn, resolution 1.95Å

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