Sandbox GGC1
From Proteopedia
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== Chymotrypsin == | == Chymotrypsin == | ||
<StructureSection load='1T8L' size='340' side='right' caption='Bovine chymotrypsin complexes with P1 BPTI variants' scene='75/752263/Intro/1'> | <StructureSection load='1T8L' size='340' side='right' caption='Bovine chymotrypsin complexes with P1 BPTI variants' scene='75/752263/Intro/1'> | ||
| - | Chymotrypsin is a protease, which is an enzyme that catalyzes the cleavage of amino acids at the carboxyl side. Chymotrypsin is composed of <scene name='75/752263/Three_chains/2'>three chains</scene> (residues 1-13 shown in maroon, 16-146 shown in blue, and 149-245 shown in gold). | + | <scene name='75/752263/Intro/1'>Chymotrypsin</scene> is a protease, which is an enzyme that catalyzes the cleavage of amino acids at the carboxyl side. Chymotrypsin is composed of <scene name='75/752263/Three_chains/2'>three chains</scene> (residues 1-13 shown in maroon, 16-146 shown in blue, and 149-245 shown in gold). |
The active site is referred to as the P1 position. The S1 binding pocket is responsible for stabilization of the P1 substrate prior to cleavage. | The active site is referred to as the P1 position. The S1 binding pocket is responsible for stabilization of the P1 substrate prior to cleavage. | ||
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1016/j.jmb.2004.09.088</ref> or to the article describing Jmol <ref>PMID:15544809</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1016/j.jmb.2004.09.088</ref> or to the article describing Jmol <ref>PMID:15544809</ref> to the rescue. | ||
| - | <scene name='75/752263/Intro/1'>Chymotrypsin</scene> | ||
== Function == | == Function == | ||
| - | <scene name='75/752263/Active_site/2'> | + | <scene name='75/752263/Active_site/2'>The active site of the bovine alpha-chymotrypsin active Site is in yellow</scene> |
== Disease == | == Disease == | ||
Revision as of 16:02, 10 April 2017
Chymotrypsin
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References
- ↑ Czapinska H, Helland R, Smalas AO, Otlewski J. Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants. J Mol Biol. 2004 Dec 3;344(4):1005-20. PMID:15544809 doi:10.1016/j.jmb.2004.09.088
- ↑ Czapinska H, Helland R, Smalas AO, Otlewski J. Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants. J Mol Biol. 2004 Dec 3;344(4):1005-20. PMID:15544809 doi:10.1016/j.jmb.2004.09.088
