5k89
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Human Calcium-Bound S100A1== | |
| - | + | <StructureSection load='5k89' size='340' side='right' caption='[[5k89]], [[Resolution|resolution]] 2.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5k89]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K89 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K89 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k89 OCA], [http://pdbe.org/5k89 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k89 RCSB], [http://www.ebi.ac.uk/pdbsum/5k89 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k89 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/S10A1_HUMAN S10A1_HUMAN]] Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Aligholizadeh, E]] | ||
| + | [[Category: McKnight, L E]] | ||
[[Category: Melville, Z]] | [[Category: Melville, Z]] | ||
[[Category: Pozharski, E]] | [[Category: Pozharski, E]] | ||
| - | [[Category: Mcknight, L.E]] | ||
[[Category: Weber, D]] | [[Category: Weber, D]] | ||
| - | [[Category: Weber, D | + | [[Category: Weber, D J]] |
| - | [[Category: | + | [[Category: Calcium]] |
| + | [[Category: Metal binding protein]] | ||
| + | [[Category: S100]] | ||
| + | [[Category: S100a1]] | ||
Revision as of 11:43, 12 April 2017
Crystal Structure of Human Calcium-Bound S100A1
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