5tk5
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human 3HAO with iron bound in the active site== | |
| - | + | <StructureSection load='5tk5' size='340' side='right' caption='[[5tk5]], [[Resolution|resolution]] 1.88Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5tk5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TK5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TK5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-hydroxyanthranilate_3,4-dioxygenase 3-hydroxyanthranilate 3,4-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.6 1.13.11.6] </span></td></tr> |
| - | [[Category: Toth, E | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tk5 OCA], [http://pdbe.org/5tk5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tk5 RCSB], [http://www.ebi.ac.uk/pdbsum/5tk5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tk5 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/3HAO_HUMAN 3HAO_HUMAN]] Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.<ref>PMID:7514594</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: 3-hydroxyanthranilate 3,4-dioxygenase]] | ||
| + | [[Category: Pidugu, L S]] | ||
| + | [[Category: Toth, E A]] | ||
| + | [[Category: 3-hydroxyanthranilate oxygenase dioxygenase]] | ||
| + | [[Category: Cupin kynurenine pathway]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 11:47, 12 April 2017
Crystal structure of human 3HAO with iron bound in the active site
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