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4y2h

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==Crystal structure of human protein arginine methyltransferase PRMT6 bound to SAH and an aryl pyrazole inhibitor==
==Crystal structure of human protein arginine methyltransferase PRMT6 bound to SAH and an aryl pyrazole inhibitor==
<StructureSection load='4y2h' size='340' side='right' caption='[[4y2h]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
<StructureSection load='4y2h' size='340' side='right' caption='[[4y2h]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=49K:N-{[5-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]METHYL}-N-METHYLETHANE-1,2-DIAMINE'>49K</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=49K:N-{[5-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]METHYL}-N-METHYLETHANE-1,2-DIAMINE'>49K</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y30|4y30]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y30|4y30]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y2h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4y2h RCSB], [http://www.ebi.ac.uk/pdbsum/4y2h PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y2h OCA], [http://pdbe.org/4y2h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y2h RCSB], [http://www.ebi.ac.uk/pdbsum/4y2h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y2h ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4y2h" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>

Revision as of 12:08, 12 April 2017

Crystal structure of human protein arginine methyltransferase PRMT6 bound to SAH and an aryl pyrazole inhibitor

4y2h, resolution 2.37Å

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