5x0y
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Complex of Snf2-Nucleosome complex with Snf2 bound to SHL2 of the nucleosome== | |
| - | + | <StructureSection load='5x0y' size='340' side='right' caption='[[5x0y]], [[Resolution|resolution]] 3.97Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5x0y]] is a 11 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X0Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5X0Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5x0x|5x0x]]</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5x0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x0y OCA], [http://pdbe.org/5x0y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x0y RCSB], [http://www.ebi.ac.uk/pdbsum/5x0y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x0y ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/H2B11_XENLA H2B11_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H32_XENLA H32_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/SNF2_YEAST SNF2_YEAST]] Involved in transcriptional activation. Catalytic component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. [[http://www.uniprot.org/uniprot/H4_XENLA H4_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chen, Z]] | ||
| + | [[Category: Li, M]] | ||
[[Category: Li, X]] | [[Category: Li, X]] | ||
[[Category: Liu, X]] | [[Category: Liu, X]] | ||
[[Category: Xia, X]] | [[Category: Xia, X]] | ||
| - | [[Category: | + | [[Category: Chromatin remodeling]] |
| - | [[Category: | + | [[Category: Nucleosome]] |
| + | [[Category: Snf2]] | ||
| + | [[Category: Structural protein-hydrolase-dna complex]] | ||
Revision as of 13:06, 19 April 2017
Complex of Snf2-Nucleosome complex with Snf2 bound to SHL2 of the nucleosome
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