Endonuclease

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 118: Line 118:
**[[4mak]] – EcCas2<br />
**[[4mak]] – EcCas2<br />
**[[4p6i]], [[4qdl]] – EcCas1 + EcCas2<br />
**[[4p6i]], [[4qdl]] – EcCas1 + EcCas2<br />
-
**[[5dlj]], [[5dqt]], [[5dqu]], [[5dqz]], [[5ds4]], [[5ds5]], [[5ds6]] – EcCas1 + EcCas2 + DNA<br />
 
**[[3s4l]] – MjCas3 – ''Methanocaldococcus jannaschii''<br />
**[[3s4l]] – MjCas3 – ''Methanocaldococcus jannaschii''<br />
**[[4qqw]] – TfCas3 – ''Thermobifida fusca''<br />
**[[4qqw]] – TfCas3 – ''Thermobifida fusca''<br />
Line 128: Line 127:
**[[3i4h]] – Cas4 - ''Pyrobaculum calidifontis''<br />
**[[3i4h]] – Cas4 - ''Pyrobaculum calidifontis''<br />
**[[4qr0]], [[4qr1]] - SpCas9 (Csn1) – ''Streptococcus pyogenes''<br />
**[[4qr0]], [[4qr1]] - SpCas9 (Csn1) – ''Streptococcus pyogenes''<br />
-
**[[4ill]], [[4ilm]] – SsCas6 + RNA - ''Sulfolobus solfataricus''<br />
 
**[[4ilr]], [[3zfv]] – SsCas6 <br />
**[[4ilr]], [[3zfv]] – SsCas6 <br />
**[[3i4h]] – PfCas6 - ''Pyrococcus furiosus''<br />
**[[3i4h]] – PfCas6 - ''Pyrococcus furiosus''<br />
-
**[[5uz9]] – PaCsa5f + Cas7f + Cas8f + anti-crispr protein + RNA<br />
 
-
**[[3pkm]] – PfCas6 + RNA<br />
 
**[[4dzd]] – EcCas6e<br />
**[[4dzd]] – EcCas6e<br />
-
**[[2y8w]], [[2y8y]], [[3qrp]], [[3qrq]], [[2qrr]] – TtCas6e (Cse3) + RNA<br />
 
-
**[[2xli]], [[2xlj]], [[2xlk]], [[4al7]] – PaCas6f (Csy4) + RNA <br />
 
-
**[[4al5]], [[4al6]] - PaCas6f (Csy4) (mutant) + RNA <br />
 
**[[4qr0]], [[4qr1]], [[4cmp]], [[4cmq]] - SpCas9 <br />
**[[4qr0]], [[4qr1]], [[4cmp]], [[4cmq]] - SpCas9 <br />
-
**[[4zt0]] - SpCas9 + RNA <br />
 
-
**[[4zt9]] - SpCas9 (mutant) + RNA <br />
 
-
**[[5f9r]] - SpCas9 + RNA + DNA<br />
 
-
**[[4oo8]], [[4un3]], [[4un4]], [[4un5]], [[5fw1]], [[5fw2]], [[5fw3]], [[5fq5]], [[5b2r]], [[5b2s]], [[5b2t]] - SpCas9 (Csn1) (mutant) + RNA + DNA<br />
 
**[[4ogc]], [[4oge]] – Cas9 II-C – ''Actinomyces naeslundii''<br />
**[[4ogc]], [[4oge]] – Cas9 II-C – ''Actinomyces naeslundii''<br />
-
**[[5x2h]], [[5x2g]] – Cas9 + RNA + DNA – ''Campylobacter jejuni''<br />
 
-
**[[5czz]] - SaCas9 (Csn1) + RNA + DNA - ''Staphylococcus aureus''<br />
 
-
**[[5axw]] - SaCas9 (Csn1) (mutant) + RNA + DNA <br />
 
-
**[[5b2o]], [[5b2p]], [[5b2q]] - FtCas9 (mutant) + RNA + DNA – ''Francisella tularensis''<br />
 
**[[3ung]], [[3ur3]], [[4doz]], [[4w8y]] – PfCas10 CMR2 subunit <br />
**[[3ung]], [[3ur3]], [[4doz]], [[4w8y]] – PfCas10 CMR2 subunit <br />
**[[4h4k]] – PfCas10 CMR2+CMR3 subunits <br />
**[[4h4k]] – PfCas10 CMR2+CMR3 subunits <br />
Line 158: Line 143:
**[[4h7a]] - TtCasB (Cse2)<br />
**[[4h7a]] - TtCasB (Cse2)<br />
**[[4tvx]] – EcCasA (Cse1) + CasE<br />
**[[4tvx]] – EcCasA (Cse1) + CasE<br />
-
**[[4u7u]] – EcCasA (Cse1) + CasB + CasC + CasD + CasE + RNA<br />
 
-
**[[4qyz]] – EcCasA (Cse1) + CasB + CasC + CasD + CasE + RNA + DNA<br />
 
**[[3qhq]] - Csn2 – ''Streptococcus agalactiae''<br />
**[[3qhq]] - Csn2 – ''Streptococcus agalactiae''<br />
**[[3toc]], [[3v7f]] – SpCsn2<br />
**[[3toc]], [[3v7f]] – SpCsn2<br />
**[[3ps0]] – SsCsa2<br />
**[[3ps0]] – SsCsa2<br />
 +
 +
*Cas ENN complex with RNA and DNA
 +
 +
**[[5dlj]], [[5dqt]], [[5dqu]], [[5dqz]], [[5ds4]], [[5ds5]], [[5ds6]] – EcCas1 + EcCas2 + DNA<br />
 +
**[[4ill]], [[4ilm]] – SsCas6 + RNA - ''Sulfolobus solfataricus''<br />
 +
**[[5uz9]] – PaCsa5f + Cas7f + Cas8f + anti-crispr protein + RNA<br />
 +
**[[3pkm]] – PfCas6 + RNA<br />
 +
**[[2y8w]], [[2y8y]], [[3qrp]], [[3qrq]], [[2qrr]] – TtCas6e (Cse3) + RNA<br />
 +
**[[2xli]], [[2xlj]], [[2xlk]], [[4al7]] – PaCas6f (Csy4) + RNA <br />
 +
**[[4al5]], [[4al6]] - PaCas6f (Csy4) (mutant) + RNA <br />
 +
**[[4zt0]] - SpCas9 + RNA <br />
 +
**[[4zt9]] - SpCas9 (mutant) + RNA <br />
 +
**[[5f9r]] - SpCas9 + RNA + DNA<br />
 +
**[[4oo8]], [[4un3]], [[4un4]], [[4un5]], [[5fw1]], [[5fw2]], [[5fw3]], [[5fq5]], [[5b2r]], [[5b2s]], [[5b2t]] - SpCas9 (Csn1) (mutant) + RNA + DNA<br />
 +
**[[5x2h]], [[5x2g]] – Cas9 + RNA + DNA – ''Campylobacter jejuni''<br />
 +
**[[5czz]] - SaCas9 (Csn1) + RNA + DNA - ''Staphylococcus aureus''<br />
 +
**[[5axw]] - SaCas9 (Csn1) (mutant) + RNA + DNA <br />
 +
**[[5b2o]], [[5b2p]], [[5b2q]] - FtCas9 (mutant) + RNA + DNA – ''Francisella tularensis''<br />
 +
**[[4u7u]] – EcCasA (Cse1) + CasB + CasC + CasD + CasE + RNA<br />
 +
**[[4qyz]] – EcCasA (Cse1) + CasB + CasC + CasD + CasE + RNA + DNA<br />
**[[5wqe]] – AaCas C2C1 + RNA – ''Alicyclobacillus acidoterrestris''<br />
**[[5wqe]] – AaCas C2C1 + RNA – ''Alicyclobacillus acidoterrestris''<br />
**[[5u34]] – AaCas C2C1 (mutant) + RNA <br />
**[[5u34]] – AaCas C2C1 (mutant) + RNA <br />

Revision as of 10:28, 30 April 2017

E. coli EcoRV endonuclease dimer (magenta, green) complex with DNA, (PDB code 1rva)

Drag the structure with the mouse to rotate

3D structures of endonuclease

Updated on 30-April-2017

References

  1. ↑ Nishino T, Morikawa K. Structure and function of nucleases in DNA repair: shape, grip and blade of the DNA scissors. Oncogene. 2002 Dec 16;21(58):9022-32. PMID:12483517 doi:http://dx.doi.org/10.1038/sj.onc.1206135
  2. ↑ Horvath P, Barrangou R. CRISPR/Cas, the immune system of bacteria and archaea. Science. 2010 Jan 8;327(5962):167-70. doi: 10.1126/science.1179555. PMID:20056882 doi:http://dx.doi.org/10.1126/science.1179555
  3. ↑ Flick KE, Jurica MS, Monnat RJ Jr, Stoddard BL. DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI. Nature. 1998 Jul 2;394(6688):96-101. PMID:9665136 doi:10.1038/27952

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Endonuclease"
Personal tools