Epoxide hydrolase
From Proteopedia
(Difference between revisions)
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**[[1qo7]], [[3g02]] – AnEH (mutant) – ''Aspergillus niger''<br /> | **[[1qo7]], [[3g02]] – AnEH (mutant) – ''Aspergillus niger''<br /> | ||
**[[2cjp]] – pEH I – potato<br /> | **[[2cjp]] – pEH I – potato<br /> | ||
| - | **[[3cxu]] – pEH (mutant) <br /> | + | **[[3cxu]], [[4ufn]], [[4ufo]], [[4ufp]], [[4uhb]], [[4y9s]] – pEH (mutant) <br /> |
| - | **[[4i19]], [[4qa9]] – EH – ''Streptomyces carzinostaticus''<br /> | + | **[[4i19]], [[4qa9]], [[4f4z]] – EH – ''Streptomyces carzinostaticus''<br /> |
*Soluble epoxide hydrolase | *Soluble epoxide hydrolase | ||
| - | **[[1s8o]], [[3i1y]], [[3i28]], [[3koo]], [[5ahx]] – hSEH – human<br /> | + | **[[1s8o]], [[3i1y]], [[3i28]], [[3koo]], [[5ahx]], [[5fp0]] – hSEH – human<br /> |
**[[1cqz]] – mSEH – mouse<br /> | **[[1cqz]] – mSEH – mouse<br /> | ||
**[[4nzz]] – BmSEH – ''Bacillus megaterium''<br /> | **[[4nzz]] – BmSEH – ''Bacillus megaterium''<br /> | ||
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**[[1nww]] – ReEH – ''Rhodococcus erythropolis''<br /> | **[[1nww]] – ReEH – ''Rhodococcus erythropolis''<br /> | ||
| - | **[[4r9k]], [[4r9l]], [[4xbx]], [[4xdw]] – ReEH (mutant)<br /> | + | **[[4r9k]], [[4r9l]], [[4xbx]], [[4xdw]], [[5cf1]], [[5cf2]], [[5jpp]] – ReEH (mutant)<br /> |
**[[1nu3]] – ReEH + valpromide <br /> | **[[1nu3]] – ReEH + valpromide <br /> | ||
| - | **[[4xbt]], [[4xdv]] – ReEH (mutant) + cyclohexanediol<br /> | + | **[[4xbt]], [[4xdv]], [[5clk]], [[5jpu]] – ReEH (mutant) + cyclohexanediol<br /> |
| - | **[[4xby]] – ReEH (mutant) + cyclopentene | + | **[[4xby]], [[5ck6]] – ReEH (mutant) + cyclopentene oxide<br /> |
| + | **[[5aif]], [[5aih]], [[5aii]] – mlEH – metagenomic library<br /> | ||
| + | **[[5aig]] – mlEH + valpromide <br /> | ||
| + | |||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 10:39, 3 May 2017
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3D Structures of epoxide hydrolase
Updated on 03-May-2017
References
- ↑ Biswal BK, Morisseau C, Garen G, Cherney MM, Garen C, Niu C, Hammock BD, James MN. The molecular structure of epoxide hydrolase B from Mycobacterium tuberculosis and its complex with a urea-based inhibitor. J Mol Biol. 2008 Sep 12;381(4):897-912. Epub 2008 Jun 17. PMID:18585390 doi:10.1016/j.jmb.2008.06.030
- ↑ Arand M, Hallberg BM, Zou J, Bergfors T, Oesch F, van der Werf MJ, de Bont JA, Jones TA, Mowbray SL. Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site. EMBO J. 2003 Jun 2;22(11):2583-92. PMID:12773375 doi:http://dx.doi.org/10.1093/emboj/cdg275
- ↑ Imig JD, Hammock BD. Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases. Nat Rev Drug Discov. 2009 Oct;8(10):794-805. doi: 10.1038/nrd2875. PMID:19794443 doi:http://dx.doi.org/10.1038/nrd2875
- ↑ Oster L, Tapani S, Xue Y, Kack H. Successful generation of structural information for fragment-based drug discovery. Drug Discov Today. 2015 Apr 28. pii: S1359-6446(15)00154-3. doi:, 10.1016/j.drudis.2015.04.005. PMID:25931264 doi:http://dx.doi.org/10.1016/j.drudis.2015.04.005
