5h45
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the C-terminal Lon protease-like domain of Thermus thermophilus RadA/Sms== | |
| - | + | <StructureSection load='5h45' size='340' side='right' caption='[[5h45]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5h45]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H45 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5H45 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5h45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h45 OCA], [http://pdbe.org/5h45 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5h45 RCSB], [http://www.ebi.ac.uk/pdbsum/5h45 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5h45 ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q5SKV2_THET8 Q5SKV2_THET8]] DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.[RuleBase:RU003555] Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.[HAMAP-Rule:MF_01498] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Fujii, Y]] | ||
| + | [[Category: Fukui, K]] | ||
| + | [[Category: Inoue, M]] | ||
| + | [[Category: Kuramitsu, S]] | ||
| + | [[Category: Masui, R]] | ||
| + | [[Category: Nakagawa, N]] | ||
| + | [[Category: Yano, T]] | ||
| + | [[Category: Dna binding protein]] | ||
| + | [[Category: Ribosomal protein s5 domain 2-like fold]] | ||
Revision as of 13:07, 4 May 2017
Crystal structure of the C-terminal Lon protease-like domain of Thermus thermophilus RadA/Sms
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